Results 161 to 170 of about 6,985 (261)
5‐Fluorouracil (5‐FU) induces cardiovascular toxicity by increasing ROS, MDA, Bax, and caspase‐3 while decreasing antioxidant defenses and Bcl‐2 levels. Apigenin and selenium enhance antioxidant capacity, restore Bcl‐2 expression, suppress apoptosis, and rebalance redox status.
Gözde Atila Uslu +4 more
wiley +1 more source
Evaluating Thioredoxin-Mediated CF<sub>o</sub>CF<sub>1</sub> Reduction Using an In Vitro Thylakoid Assay. [PDF]
Sekiguchi T, Yoshida K, Hisabori T.
europepmc +1 more source
ABSTRACT Organotin (IV) compounds are known to induce apoptosis via the intrinsic mitochondrial pathway, which is a key mechanism of effective anticancer therapy. Their ability to selectively promote apoptotic cell death highlights their potential as chemotherapeutic agents. In this study, the in vitro effects of two triorganotin compounds, tributyltin
Dana Strouhalova +3 more
wiley +1 more source
Role of Different Enzymes in H<sub>2</sub>O<sub>2</sub> Neutralization and Cellular Radioresistance, Estimated by Mathematical Modeling. [PDF]
Ciesielska S +3 more
europepmc +1 more source
ABSTRACT Cadmium (Cd2+) contamination in agricultural soils has been reported to pose risks to crop productivity, food safety, and human health. This review synthesizes current knowledge on the mechanisms by which essential (S, Zn, Fe, Mg, K, Ca) and beneficial (Si, Se, rare earth elements) elements mitigate Cd2+ toxicity in plants.
Maria Manzoor, Karl Hermann Mühling
wiley +1 more source
Thioredoxin System in Insects: Uncovering the Roles of Thioredoxins and Thioredoxin Reductase beyond the Antioxidant Defences. [PDF]
Gřešková A, Petřivalský M.
europepmc +1 more source
Role of ClpX and MsrA/B in the Oxidative and Cell Wall Stress Response in Bacillus anthracis Sterne
Methionine sulfoxide reductase (msrA/B) is an oxidative response enzyme that reduces oxidized methionine residues to maintain protein function. Surprisingly, loss of MsrA/B does not increase sensitivity to hydrogen peroxide or paraquat‐induced oxidative stress in Bacillus anthracis Sterne.
Aeron B. Pennington +5 more
wiley +1 more source
Thioredoxin 1 moonlights as a chaperone for an interbacterial ADP-ribosyltransferase toxin. [PDF]
Dumont B +4 more
europepmc +1 more source
Glucose Transporter 1 in Health and Disease
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai +3 more
wiley +1 more source
A structural perspective on α-glucan catabolism in oxygenic phototrophs. [PDF]
Doello S, Shvarev D.
europepmc +1 more source

