Results 181 to 190 of about 6,985 (261)

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Deciphering the Function and Structure of PA1216 as an S‐Adenosyl‐l‐Methionine Binding Protein Using Differential Scanning Fluorimetry and Circular Dichroism

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract Microbes produce bioactive secondary metabolites as toxins, pigments, or virulence factors. These specialized compounds are produced by nonribosomal peptide synthetases (NRPS), polyketide synthases (PKS), or hybrid NRPS/PKS pathways. The genes encoding NRPS and PKS reside in biosynthetic gene clusters (BGCs), some of which have no identified ...
Amaan M. Fruitwala   +4 more
wiley   +1 more source

Integrated analysis with iCM‐SANS, SAXS and MD simulations for dynamics of multi‐domain proteins

open access: yesJournal of Applied Crystallography, Volume 59, Issue 4, Page 1270-1281, August 2026.
Segmental deuteration, combined with inverse contrast‐matching small‐angle neutron scattering (iCM‐SANS) and small‐angle X‐ray scattering (SAXS), provides structural constraints that improve discrimination of conformation ensembles of multi‐domain proteins derived from molecular dynamics (MD) simulations.Multi‐domain proteins (MDPs) adopt diverse ...
Aya Okuda   +10 more
wiley   +1 more source

South African Herbal Teas and Diabetes‐Mediated Mitochondrial Dysfunction: Emerging Evidence and Mechanistic Insights

open access: yesJournal of Food Science, Volume 91, Issue 8, August 2026.
ABSTRACT Type 2 diabetes mellitus (T2DM) is a central component of the metabolic syndrome (MetS) and is associated with underlying mitochondrial dysfunction. Disruption of mitochondrial homeostasis impairs cellular energy metabolism and contributes to the overproduction of reactive oxygen species (ROS), leading to oxidative stress, chronic inflammation,
Shanika Reddy   +3 more
wiley   +1 more source

Bacterial Volatile Organic Compounds Mediate a Cooperative Relationship Between Bacteria and Plants Under Heavy Metal Stress

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
In this brief report, we propose a scenario in which bacterial volatile organic compound (BVOC)‐mediated communication with plants can be interpreted as a form of plant–microbe cooperation under heavy metal stress. Different VOCs are emitted depending on bacterial stress states, and VOCs from heavy metal‐stressed bacteria modulate plant defense ...
Anahita Barghi   +2 more
wiley   +1 more source

Exploration of Length and Hydrophobicity Requirements for Optimal α‐Amylase Secretion in Bacillus subtilis Based on Rational Design

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
Rational engineering of the B. subtilis α‐amylase signal peptide (SPAmyE) utilizing an in silico modelling approach to design a shorter, but functional SPAmyE. A synthetic SPAmyE with approximately 60% of the original length was generated and facilitated secretion of AmyE to comparable levels as the native SPAmyE.
Dicky A. Pranoto   +5 more
wiley   +1 more source

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