Role of thioredoxin reductase (TrxB) in oxidative stress response of <i>Francisella tularensis</i> live vaccine strain. [PDF]
Higgs M +4 more
europepmc +1 more source
ABSTRACT Santamarine (SAMA), a Michelia compressa‐derived sesquiterpene lactone, exhibits ROS‑mediated anticancer activity; however, its potential mechanisms and synergy with cisplatin in oral cancer have not been explored. This study investigated SAMA and cisplatin's combined effects and underlying ROS/MAPK mechanisms of action on oral cancer cells ...
Hsin‐I. Lu +8 more
wiley +1 more source
Nucleoredoxin 1 in Wheat: Genomic Analysis and Demonstration of Its Role in Redox Homeostasis and Stress Resilience. [PDF]
Ghafoor MS +7 more
europepmc +1 more source
Multi‐Omics Analyses Elucidate the Venom Components of the Wasp Vespa mandarinia
The wasp Vespa mandarinia was widely reared in Yunnan province. The venom was responsible for their aggressive behavior. Tweety proteases, hyaluronidase, venom dipeptidyl peptidase 4, and phospholipase A1 and A2 isozyme were identified. In addition, organic heterocyclic compounds, organic acids, and derivatives were found.
Yuan‐Chong Shi +4 more
wiley +1 more source
Functional relationship of atypical thioredoxins with NADPH-thioredoxin reductase C and 2-Cys peroxiredoxins in Arabidopsis chloroplasts. [PDF]
Jiménez-López J +4 more
europepmc +1 more source
An Update on Oxidative Stress and Redoxins in Pancreatitis. [PDF]
Assi M.
europepmc +1 more source
TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD
This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley +1 more source
Systematic determination of disulfide bond reduction potentials reveals a nonequilibrium redox hierarchy in cyanobacteria. [PDF]
Tanaka K, Kondo A, Hasunuma T.
europepmc +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source
Redox Modulation in Therapy of Cancer: Some Pros and Cons. [PDF]
Zorova LD +9 more
europepmc +1 more source

