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Hydrogen bonding in thiosemicarbazide

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1970
In a recent paper (Domiano, Fava Gasparri, Nardelli & Sgarabotto, 1969, DGNS) the crystal-structure analysis of thiosemicarbazide, carried out by photographic methods, was reported (final R=9 .9%) . The positions of the hydrogen atoms were postulated from consideration of the hybridization of the nitrogen atoms and the packing interactions, no direct ...
G. D. Andreetti   +4 more
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Structure of 4-(3-chlorophenyl)thiosemicarbazide

Acta Crystallographica Section C Crystal Structure Communications, 1991
C7H8ClN3S, Mr = 201.67, monoclinic, P21/c, a = 6.914 (5), b = 4.304 (4), c = 30.306 (3) A, beta = 94.66 (3) degrees, V = 899.0 (1) A3, Z = 4, Dm = 1.54, Dx = 1.490 Mg m-3, lambda (Cu K alpha) = 1.5418 A, mu = 5.54 mm-1, F(000) = 416, T = 298 K, final R = 0.048 for 1219 observed reflections.
D, Chattopadhyay   +4 more
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Effects of Thiosemicarbazide on Audiogenic Seizures

Psychological Reports, 1966
35 male albino rats were tested for audiogenic seizures and then divided into 5 time-delay groups. These time delays preceded bell-can stimulations following the administration of thiosemicarbazide. It was found that 1-hr. and 5-hr. delays resulted in an increase in the number of seizures.
E E, Benson, H C, Salzberg
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ChemInform Abstract: Thiosemicarbazides in Heterocyclization

ChemInform, 2011
AbstractReview: 142 refs.
Alaa A. Hassan, Ahmed M. Shawky
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Susceptibility to audiogenic seizure induced by thiosemicarbazide

Experimental Neurology, 1969
Abstract Rats, cats, and monkeys were subjected to audiogenic stimuli after the administration of thiosemicarbazide (TSC). The treated rats responded to audiogenic stimulation with episodic running behavior (ERB) with or without convulsion (C), the most effective dosage being 4.4 mg/kg.
J A, Wada, T, Asakura
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Thiosemicarbazid-1-ium Dihydrogenphosphate

Acta Crystallographica Section C Crystal Structure Communications, 1998
Thio­semicarbazid-1-ium dihydrogenphosphate, CH6N3S+.H2PO4−, unlike the semicarbazide complex compounds, does not exhibit temperature-dependent ferroelectric properties. X-ray structure determination at room temperature has shown that the crystal is centrosymmetric, space group C2/c, and thermal mobility of the structural units is relatively low.
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Biological Activity of 4-(4-Bromophenyl)thiosemicarbazide

Acta Crystallographica Section C Crystal Structure Communications, 1996
The two molecules (A and B) in the asymmetric unit of the title compound, C7H8BrN3S, display different conformation. In both molecules, the S atom is trans to the NH2 group. The Br atoms of the two molecules approach each other at a distance of 3.573(2) A.
S, Seth   +4 more
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Menthone Semicarbazides and Thiosemicarbazides as Anticonvulsant Agents

Medicinal Chemistry, 2010
A series of novel (+/-) 3-menthone semi carbazides (1-7) and thiosemicarbazides synthesized using an appropriate synthetic route and characterized by thin layer chromatography and spectral analysis. The anticonvulsant activity of synthesized compounds was established after intraperitoneal administration in three seizure models in mice which include ...
Jainendra, Jain   +3 more
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Thermodynamics of silver-thiosemicarbazide complexation

The Journal of Chemical Thermodynamics, 1976
Abstract The stability constants of the complexes formed by the silver ion with thiosemicarbazide ( tsc ) are determined by a potentiometric method using a silver electrode, in a wide range of silver-ion overall concentration (from 10−4 to 9 × 10−3 mol dm−3).
Guy Berthon, Torsten Berg
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Some Biologically Active Poly(thiosemicarbazides)

Annals of the New York Academy of Sciences, 1985
L G, Donaruma, R J, Warner
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