Results 1 to 10 of about 18,261 (204)
Cytotoxic Properties of 1,3,4-Thiadiazole Derivatives—A Review [PDF]
Molecules, 2020 During recent years, small molecules containing five-member heterocyclic moieties have become the subject of considerable growing interest for designing new antitumor agents. One of them is 1,3,4-thiadiazole. This study is an attempt to collect the 1,3,4-
Monika Wujec +2 more
exaly +6 more sources
Antimicrobial Activity of 1,3,4-Thiadiazole Derivatives [PDF]
PharmaceuticalsThe 1,3,4-thiadiazole core has attracted significant attention due to its unique electronic structure, physicochemical properties, and wide-ranging pharmacological potential.
Sebastian Górecki +2 more
doaj +6 more sources
Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold
Chemistry, 2022 The chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities.
Sumitra Nain, Sarvesh Paliwal
exaly +4 more sources
Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole N-glycosides [PDF]
Molecules, 2019 New 1,3,4-thiadiazole thioglycosides linked to substituted arylidine systems were synthesized via glycosylation of the prepared 1,3,4-thiadiazole thiol compounds.
Fahad M. Alminderej +4 more
doaj +4 more sources
1,3,4-Thiadiazole Scaffold: As Anti-Epileptic Agents [PDF]
Frontiers in Chemistry, 2022 A wide range of biological activities is exhibited by 1,3,4-thiadiazole moiety such as antidiabetic, anticancer, anti-inflammatory, anticonvulsant, antiviral, antihypertensive, and antimicrobial.
Tulika Anthwal, Sumitra Nain
doaj +3 more sources
Synthesis of 1,3,4-Thiadiazole Derivatives and Their Anticancer Evaluation. [PDF]
Int J Mol Sci, 2023 Thiadiazole derivatives have garnered significant attention in the field of medicinal chemistry due to their diverse pharmacological activities, including anticancer properties. This article presents the synthesis of a series of thiadiazole derivatives and investigates their chemical characterization and potential anticancer effects on various cell ...
Stecoza CE +8 more
europepmc +3 more sources
Recent Developments of 1,3,4-Thiadiazole Compounds as Anticancer Agents [PDF]
PharmaceuticalsThe World Health Organization has recently underlined the increasing global burden of cancer, with a particularly alarming impact on underserved populations.
Serena Indelicato +3 more
doaj +2 more sources
Ultrasonics Sonochemistry, 2009 Novel substituted 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) were synthesized from reaction of 1-methyl-5-oxo-3-phenyl-2-pyrazolin-4-thiocarbox-anilide with a series of different hydrazonyl halides or N,N'-diphenyl-oxalodihydrazonoyl dichloride. The reactions were carried out under both conventional and ultrasonic irradiation conditions.
Tamer S. Saleh, Mohamed F. Mady
exaly +3 more sources
Theoretical Study of Interaction Between Thiadiazole Derivatives on Fe(110) Surface [PDF]
Journal of Chemistry Letters, 2023 The theoretical performance of 4-methoxyphenyl-1,3,4-thiadiazole (AMPT), 2-Amino-5-(4-chlorophenyl)-1,3,4-thiadiazole (ACPT) and 2-amino-5-phenyl-1,3,4-thiadiazole (APT) as inhibitors of iron corrosion was assessed with a view of determining the ...
Thomas Nyijime +3 more
doaj +1 more source
Medicine in Drug Discovery, 2023 Significant progress in understanding cancer pathogenesis, it remains one of the leading causes of death after cardiovascular diseases. Similarly viral infections have emerged from wildlife or re-emerged, generating serious threats to the global health ...
Davinder Kumar +6 more
doaj +1 more source