4α,14α,Dimethyl-5α-cholest-8-en-3-one thiosemicarbazone
n ...
Noureddine Mazoir +3 more
doaj +1 more source
Heterocyclic dithiocarbazate iron chelators: Fe coordination chemistry and biological activity [PDF]
The iron coordination and biological chemistry of a series of heterocyclic dithiocarbazate Schiff base ligands is reported with regard to their activity as Fe chelators for the treatment of Fe overload and also cancer.
Ali, Mohammad Akbar +7 more
core +1 more source
A library of cationic dinuclear Ru(II)‐η⁶‐arene analogues was developed to assess how overall charge and Ru–Ru distance influence DNA binding noncovalent interactions and cytotoxicity. NMR studies showed multiple binding modes with the B‐form DNA oligonucleotide d(5΄‐CGCGAATTCGCG‐3΄)2, while the complexes displayed micromolar IC50 values against MCF‐7,
Dimitrios Thomos +5 more
wiley +1 more source
2-Hydroxy-4-methoxybenzaldehyde thiosemicarbazone
The title Schiff base compound, C9H11N3O2S, was prepared by the reaction of equimolar quantities of 2-hydroxy-4-methoxybenzaldehyde with thiosemicarbazide in methanol.
Yu-Mei Hao
doaj +1 more source
Cytotoxicity of Metal Based Anticancer Active Complexes and their Targeted Delivery using Nanoparticles [PDF]
Use of metal based anticancer medication began with the clinical approval of cisplatin in 1978. Research led to the development of six platinum based drug candidates which are in use around the world.
Pramanik, Anup Kumar
core +1 more source
Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties [PDF]
Pursuing our recent outcomes regarding the antifungal activity of N-substituted 1,3-thiazolidin-4-ones, we synthesized thirty-six new derivatives introducing aliphatic, cycloaliphatic and heteroaromatic moieties at N1-hydrazine connected with C2 position
Abdurrahman, Aktumsek +10 more
core +1 more source
The inhibitive effects of 2-acetylpyridine 4-ethyl-3-thiosemicarbazone (HAcETSc) and dichlorophenyltin(IV) 2-acetylpyridine 4-ethyl-3-thiosemicarbazone (Sn(HAcETSc)PhenCl2) for mild steel in 1 M HCl solution at different concentrations were investigated ...
Nur Nadira Hazani +3 more
doaj +1 more source
2,5-Dimethoxybenzaldehyde thiosemicarbazone
In the title molecule, C10H13N3O2S, the dihedral angle between benzene and –N—C(=S)—N—N=C– planes is 9.20 (6)°.
S. M. Dharmaprakash +4 more
doaj +1 more source
The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms [PDF]
Background Neuroblastoma is a relatively common and highly belligerent childhood tumor with poor prognosis by current therapeutic approaches. A novel anti-cancer agent of the di-2-pyridylketone thiosemicarbazone series, namely di-2-pyridylketone 4,4 ...
Danuta S. Kalinowski +5 more
core +3 more sources
Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade +4 more
wiley +1 more source

