Results 71 to 80 of about 7,932 (222)

4-Methyl-2-phenylpent-2-enal thiosemicarbazone

IUCrData, 2019
In the title compound, C13H17N3S, the dihedral angle between the thiosemicarbazone moiety [maximum deviation = 0.055 (2) Å] and the phenyl ring is 53.15 (12)°.
L. Anitha, S. R. Saritha, S. R. Layana, M. Sithambaresan, M. R. Sudarsanakumar   +4 more
doaj   +1 more source

Unraveling the role of TP53 mutations in myeloproliferative neoplasms: Molecular mechanisms of leukemic transformation

HemaSphere, Volume 10, Issue 3, March 2026.
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito, Paula Sabbo Bernardo, Jean‐Edouard Martin, Caroline Marty, Isabelle Plo, Iléana Antony‐Debré, Bárbara da Costa Reis Monte‐Mór   +6 more
wiley   +1 more source

Synthesis and biological evaluation of thiosemicarbazone derivatives

, 2022
In this study, firstly, 22 thiosemicarbazone derivatives (3a-y) were synthesized. Then, ADME parameters, pharmacokinetic properties, drug-like structures, and suitability for medicinal chemistry of these molecules were studied theoretically by using ...
CEYLAN, MUSTAFA, Budak, Yakup, Gurdere, Meliha Burcu, Meliha Burcu Gürdere, Ümit M. Koçyiğit, Koçyiğit,Ümit M., Gürdere,Meliha B., KOÇYİĞİT, ÜMİT MUHAMMET, Budak,Yakup, Murat Doğan, Doğan, Murat, Ceylan,Mustafa, Mustafa Ceylan, Yakup Budak   +13 more
core   +1 more source

Electrochemical Studies of Thiosemicarbazone Derivative and Its Tin(IV) Complex as Corrosion Inhibitor for Mild Steel in 1 M Hydrochloric Acid

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2019
The inhibitive effects of 2-acetylpyridine 4-ethyl-3-thiosemicarbazone (HAcETSc) and dichlorophenyltin(IV) 2-acetylpyridine 4-ethyl-3-thiosemicarbazone (Sn(HAcETSc)PhenCl2) for mild steel in 1 M HCl solution at different concentrations were investigated ...
Nur Nadira Hazani, Yusairie Mohd, Sheikh Ahmad Izaddin Sheikh Mohd Ghazali, Nur Nadia Dzulkifli   +3 more
doaj   +1 more source

4α,14α,Dimethyl-5α-cholest-8-en-3-one thiosemicarbazone

Molbank, 2006
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Noureddine Mazoir, My Youssef Ait Itto, Matías Reina Artiles, Ahmed Benharref   +3 more
doaj   +1 more source

2-Hydroxy-4-methoxybenzaldehyde thiosemicarbazone

Acta Crystallographica Section E, 2010
The title Schiff base compound, C9H11N3O2S, was prepared by the reaction of equimolar quantities of 2-hydroxy-4-methoxybenzaldehyde with thiosemicarbazide in methanol.
Yu-Mei Hao
doaj   +1 more source

Polysaccharide‐Coated ETCA Nanoparticles Containing the Methoxyl Substituted Indole‐Thiazole Derivative and Their Antiproliferative Activity in Breast Cancer Cells

Journal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.
ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares, Iago Dillion Lima Cavalcanti, Iranildo José da Cruz‐Filho, Mariane Cajubá de Britto Lira Nogueira, Maria do Carmo Alves de Lima   +4 more
wiley   +1 more source

2,5-Dimethoxybenzaldehyde thiosemicarbazone

Acta Crystallographica Section E, 2008
In the title molecule, C10H13N3O2S, the dihedral angle between benzene and –N—C(=S)—N—N=C– planes is 9.20 (6)°.
S. M. Dharmaprakash, P. S. Patil, E. Deepak D'Silva, Samuel Robinson Jebas, Hoong-Kun Fun   +4 more
doaj   +1 more source

Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn(II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy

We implemented isosteric replacement of sulfur to selenium in a novel thiosemicarbazone (PPTP4c4mT) to create a selenosemicarbazone (PPTP4c4mSe) that demonstrates potentiated anticancer efficacy and selectivity.
Suleymanoglu, Mediha, Harmer, Jeffrey R, Richardson, Vera, Bernhardt, Paul V, Gholam Azad, Mahan, Wijesinghe, Tharushi P, Kaya, Busra, Zhao, Xiao, Dharmasivam, Mahendiran, Richardson, Des R   +9 more
core   +1 more source

Isatin thiosemicarbazone ligands and their characterization by NMR spectroscopy: Formation of their Cu(II) metal complexes [PDF]

, 2018
A new series of Isatin Thiosemicarbazone (I-TSC) ligands were synthesized. The ligands were synthesized with the following substituent groups: methyl thiosemicarbazone, ethyl thiosemicarbazone, tert-butyl thiosemicarbazone, phenyl thiosemicarbazone, and ...
Buckner, Arielle, Bowman, Sarah
core