Results 71 to 80 of about 12,825 (226)

4α,14α,Dimethyl-5α-cholest-8-en-3-one thiosemicarbazone

open access: yesMolbank, 2006
n ...
Noureddine Mazoir   +3 more
doaj   +1 more source

Heterocyclic dithiocarbazate iron chelators: Fe coordination chemistry and biological activity [PDF]

open access: yes, 2012
The iron coordination and biological chemistry of a series of heterocyclic dithiocarbazate Schiff base ligands is reported with regard to their activity as Fe chelators for the treatment of Fe overload and also cancer.
Ali, Mohammad Akbar   +7 more
core   +1 more source

DNA Noncovalent Interactions of Dinuclear η6‐Arene Ru(II) Complexes: Influence of Complex Charge and Bridging Ligand Length on DNA Binding Mode and Cytotoxic Activity

open access: yesChemistry – A European Journal, Volume 31, Issue 71, December 17, 2025.
A library of cationic dinuclear Ru(II)‐η⁶‐arene analogues was developed to assess how overall charge and Ru–Ru distance influence DNA binding noncovalent interactions and cytotoxicity. NMR studies showed multiple binding modes with the B‐form DNA oligonucleotide d(5΄‐CGCGAATTCGCG‐3΄)2, while the complexes displayed micromolar IC50 values against MCF‐7,
Dimitrios Thomos   +5 more
wiley   +1 more source

2-Hydroxy-4-methoxybenzaldehyde thiosemicarbazone

open access: yesActa Crystallographica Section E, 2010
The title Schiff base compound, C9H11N3O2S, was prepared by the reaction of equimolar quantities of 2-hydroxy-4-methoxybenzaldehyde with thiosemicarbazide in methanol.
Yu-Mei Hao
doaj   +1 more source

Cytotoxicity of Metal Based Anticancer Active Complexes and their Targeted Delivery using Nanoparticles [PDF]

open access: yes, 2016
Use of metal based anticancer medication began with the clinical approval of cisplatin in 1978. Research led to the development of six platinum based drug candidates which are in use around the world.
Pramanik, Anup Kumar
core   +1 more source

Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties [PDF]

open access: yes, 2016
Pursuing our recent outcomes regarding the antifungal activity of N-substituted 1,3-thiazolidin-4-ones, we synthesized thirty-six new derivatives introducing aliphatic, cycloaliphatic and heteroaromatic moieties at N1-hydrazine connected with C2 position
Abdurrahman, Aktumsek   +10 more
core   +1 more source

Electrochemical Studies of Thiosemicarbazone Derivative and Its Tin(IV) Complex as Corrosion Inhibitor for Mild Steel in 1 M Hydrochloric Acid

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2019
The inhibitive effects of 2-acetylpyridine 4-ethyl-3-thiosemicarbazone (HAcETSc) and dichlorophenyltin(IV) 2-acetylpyridine 4-ethyl-3-thiosemicarbazone (Sn(HAcETSc)PhenCl2) for mild steel in 1 M HCl solution at different concentrations were investigated ...
Nur Nadira Hazani   +3 more
doaj   +1 more source

2,5-Dimethoxybenzaldehyde thiosemicarbazone

open access: yesActa Crystallographica Section E, 2008
In the title molecule, C10H13N3O2S, the dihedral angle between benzene and –N—C(=S)—N—N=C– planes is 9.20 (6)°.
S. M. Dharmaprakash   +4 more
doaj   +1 more source

The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms [PDF]

open access: yes, 2016
Background Neuroblastoma is a relatively common and highly belligerent childhood tumor with poor prognosis by current therapeutic approaches. A novel anti-cancer agent of the di-2-pyridylketone thiosemicarbazone series, namely di-2-pyridylketone 4,4 ...
Danuta S. Kalinowski   +5 more
core   +3 more sources

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade   +4 more
wiley   +1 more source

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