Results 81 to 90 of about 12,825 (226)

1H-Indole-3-carbaldehyde thiosemicarbazone

Acta Crystallographica Section E, 2008
The molecules of the title compound, C10H10N4S, are linked by N—Hindole...S hydrogen bonds to form a linear hydrogen-bonded chain. There are two independent molecules in the asymmetric unit.
Seik Weng Ng, Hapipah M. Ali, Razali M. Rizal   +2 more
doaj   +1 more source

Nitrofurazone and its nitroheterocyclic analogues: a study of the electrochemical behavior in aqueous medium [PDF]

, 2013
The biological action of drugs with potential antichagasic activities can be better understood by knowing their reduction mechanism. For this proposal, the electrochemical reduction of nitrofurazone (NF) and its analogues, nitrofurfurilidene ...
Brito, Charles de Lima, Ferreira, Elizabeth Igne, La-Scalea, Mauro Aquiles, Trossini, Gustavo Henrique Goulart   +3 more
core   +1 more source

Design, Synthesis, In Silico Absorption, Distribution, Metabolism, and Elimination and Molecular Docking Studies of Thiazole‐Based Furan Derivatives, and Their Biological Evaluation for Alzheimer Disease Therapy

ChemistryOpen, Volume 14, Issue 12, December 2025.
GA: Oxidative stress plays a critical role in Alzheimer's disease (AD) by promoting Aβ plaque accumulation and tau pathology, accelerating neurodegeneration. Elevated reactive oxygen species contribute to cognitive decline through extensive oxidative damage.
Abdüllatif Karakaya, Ulviye Acar Çevik, Betül Kaya, Bilge Çiftçi, Adem Necip, Mesut Işık, Şükrü Beydemir, Yusuf Özkay, Zafer Asım Kaplancıklı   +8 more
wiley   +1 more source

5-Bromo-1H-indole-3-carbaldehyde thiosemicarbazone

Acta Crystallographica Section E, 2008
In the essentially planar title molecule, C10H9BrN4S, the C=N double bond is in a trans configuration. In the crystal structure, the S atom acts as a hydrogen-bond acceptor for the aromatic NH, aliphatic NH and terminal NH2 groups of three symmetry ...
Seik Weng Ng, Hapipah Mohd. Ali, Mohd. Razali Rizal   +2 more
doaj   +1 more source

Synthesis and structural characterization of a disulphide-bridged tetranuclear palladium(II) complex derived from 3,5-diacetyl 1,2,4-triazole bis(4-ethylthiosemicarbazone) [PDF]

, 2007
NOTICE: this is the author’s version of a work that was accepted for publication in Inorganic Chemistry Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality ...
Matesanz, Ana I., Pastor, César J., Souza, Pilar   +2 more
core   +2 more sources

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

ChemistryOpen, Volume 14, Issue 11, November 2025.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel, Amr S. Abouzied, Magdi E. A. Zaki, Abdulwahab Alamri, Basant Farag, Saad Alqarni, Sobhi M. Gomha   +6 more
wiley   +1 more source

Recent progress in thiocarbazone metal complexes for cancer therapy via mitochondrial signalling pathway

Frontiers in Chemistry
Mitochondria are the energy factories of cells and are important targets for the development of novel tumour treatment strategies owing to their involvement in processes such as apoptosis, oxidative stress, and metabolic programming.
Yunyun Zheng, Hangyi An, Jinxu Qi, Jiaming Li   +3 more
doaj   +1 more source

Benzaldehyde thiosemicarbazone

Acta Crystallographica Section E, 2008
The title compound, C8H9N3S, contains two molecules in the asymmetric unit. One molecule is close to being planar (r.m.s. deviation from the mean plane = 0.06 Å for the non-H atoms), while the other exhibits a dihedral angle of 21.7 (1)&#
Xiu-Ping Ju, Ji-Dong Zhang, Yan Qiao, Lingqian Kong   +3 more
doaj   +1 more source

Investigation of potential anti-radiation and anti-neoplastic compounds related to plant growth regulators second quarterly progress report, 1 oct. 1964 - 1 jan. 1965 [PDF]

Antiradiation and antineoplastic compounds related to plant growth regulators - cytotoxic effects and radiation ...
Norman, D., Schultz, R. D.
core   +1 more source

Unveiling Benzoxazole‐Substituted Thiazolyl‐Pyrazole Derivatives Inducing Apoptosis by Targeting β‐Tubulin and Caspase‐3

ChemMedChem, Volume 20, Issue 17, September 11, 2025.
BP(1‐6) compounds designed from Benzoxazole and Thiazolyl‐Pyrazole scaffolds exhibited potent antitubulin and caspase‐3 activity in MDA‐MB‐231 cells. BP‐6 notably triggered apoptosis and disrupted cell proliferation. Docking studies validated strong binding affinities of BP‐2 and BP‐6 toward β‐tubulin and caspase‐3, suggesting promising therapeutic ...
Burak Kuzu, Mustafa Cakir, Eda Acikgoz, Mehmet Abdullah Alagoz   +3 more
wiley   +1 more source