Results 81 to 90 of about 7,932 (222)

Coordinative properties of the pyridine-2-carbaldehyde thiosemicarbazone ligand towards Ni(II)

, 2014
Three crystal structures of Ni compounds containing bis(pyridine-2-carbaldehyde thiosemicarbazone) ligand (HL), namely (pyridine-2-carbaldehyde thiosemicarbazonato)(pyridine-2-carbaldeyde thiosemicarbazone) nickel(II) nitrate hydrate [Ni(HL)L][NO3 ...
PREDIERI, Giovanni, S. Canossa, GRAIFF, Claudia   +2 more
core   +1 more source

1H-Indole-3-carbaldehyde thiosemicarbazone

Acta Crystallographica Section E, 2008
The molecules of the title compound, C10H10N4S, are linked by N—Hindole...S hydrogen bonds to form a linear hydrogen-bonded chain. There are two independent molecules in the asymmetric unit.
Seik Weng Ng, Hapipah M. Ali, Razali M. Rizal   +2 more
doaj   +1 more source

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li, Yibo He, Yang Zhang, Lining Arnold Ju, Yao Wang, Jianxuan Zhou, Yinying Chai, Xuhui Hui, ShiYuan Tong, Si Zhang, Yanli Tan, Yinyan Wang   +11 more
wiley   +1 more source

Recent progress in thiocarbazone metal complexes for cancer therapy via mitochondrial signalling pathway

Frontiers in Chemistry
Mitochondria are the energy factories of cells and are important targets for the development of novel tumour treatment strategies owing to their involvement in processes such as apoptosis, oxidative stress, and metabolic programming.
Yunyun Zheng, Hangyi An, Jinxu Qi, Jiaming Li   +3 more
doaj   +1 more source

5-Bromo-1H-indole-3-carbaldehyde thiosemicarbazone

Acta Crystallographica Section E, 2008
In the essentially planar title molecule, C10H9BrN4S, the C=N double bond is in a trans configuration. In the crystal structure, the S atom acts as a hydrogen-bond acceptor for the aromatic NH, aliphatic NH and terminal NH2 groups of three symmetry ...
Seik Weng Ng, Hapipah Mohd. Ali, Mohd. Razali Rizal   +2 more
doaj   +1 more source

New Quinoline Kinase Inhibitors With Good Selectivity for NAK Kinases and Anti‐Tumor Activity Against Ewing Sarcoma

Archiv der Pharmazie, Volume 359, Issue 1, January 2026.
Focusing on the discovery of new therapeutics for childhood cancer, novel quinoline derivatives were synthesized and demonstrated activity against Ewing sarcoma. A target search was performed against a panel of kinases, and the compounds showed selectivity for the NAK family, mainly GAK, which was confirmed by enzyme kinetic assays.
Caroline de Bem Gentz, Thais Helena Maciel Fernandes, Marcela Silva Lopes, Lewis Elson, Andreas Krämer, Lucas Rodrigo de Souza, Isadora Serraglio Fortes, Geórgia Silva Pinto, Martha Cestari Silva Martins, Henrique Barros de Lima, André da Silva Santiago, Lauro José Gregianin, Katlin Brauer Massirer, Mário Henrique Bengtson, Rafael Roesler, Stefan Knapp, Stefan A. Laufer, Saulo Fernandes de Andrade   +17 more
wiley   +1 more source

A square planar cobalt(II)-thiosemicarbazone complex. Synthesis, characterization, antiviral and anti-inflammatory potential

Considering the possible antiviral effect of cobalt compounds and known pharmacological potential of thiosemicarbazones, a new combination containing cobalt(II) ions and tetradentate thiosemicarbazone was synthesized and structurally analyzed.
Sahin, Onur, Ulkuseven, Bahri, Atasever-Arslan, Belkis, Kaya, Busra   +3 more
core   +1 more source

Mixed Bis(thiosemicarbazone) Ligands for the Preparation of Copper Radiopharmaceuticals:  Synthesis and Evaluation of Tetradentate Ligands Containing Two Dissimilar Thiosemicarbazone Functions

, 2016
A series of four “mixed” bis(thiosemicarbazone) keto aldehyde derivatives containing dissimilar thiosemicarbazone functions were synthesized and evaluated as ligands for preparation of radiocopper-labeled radiopharmaceuticals.
John K. Lim (2663104), Carla J. Mathias (2682121), Mark A. Green (1292190)   +2 more
core   +1 more source

Structural Studies of 2,6-Diacetyl- and 2,6-Diformylpyridine Bis(thiosemicarbazones)

Journal of the Brazilian Chemical Society, 2002
Although a large number of crystal structures of heterocyclic thiosemicarbazones have recently appeared in the literature, few structures of heterocyclic bis(thiosemicarbazones) or their metal complexes have been reported.
Brown Christine A., Kaminsky Werner, Claborn Kacey A., Goldberg Karen I., West Douglas X.   +4 more
doaj  

Avaliação do potencial anticorrosivo de tiossemicarbazonas solubilizadas em microemulsão Evaluation of anticorrosive effectiveness of thiosemicarbazones solubilized in a microemulsion system

Química Nova, 2013
In this paper, thiosemicarbazones 4-N-cinnamoyl-thiosemicarbazone (CTSC), 4-N-(2'-methoxycinnamoyl)-thiosemicarbazone (MCTSC), and 4-N-(4'-hydroxy-3'-methoxybenzoyl)- thiosemicarbazone (HMBTSC) were solubilized in an oil-in-water (O/W) microemulsion ...
Elaine Cristina M. de Moura, Adna Dornelles N. Souza, Cátia Guaraciara F. T. Rossi, Djalma R. da Silva, Maria Aparecida M. Maciel, Aurea Echevarria, Myrtes S. S. Bellieny   +6 more
doaj