Results 51 to 60 of about 12,825 (226)

Synthesis and in vitro Biological Assessments of Novel Thiazole-Based Thiosemicarbazone Complexes

Düzce Üniversitesi Bilim ve Teknoloji Dergisi
In the present work, novel heterocyclic thiazole-based thiosemicarbazone Ag(I) complexes (Hc1, Hc2, Hc3) were obtained using the template method. The structures of synthesized thiosemicarbazone compounds were determined by some spectroscopic techniques ...
Dilek Nartop, Elvan Hasanoğlu Özkan, Hatice Öğütçü, Nurdan Kurnaz Yetim   +3 more
doaj   +1 more source

Synthesis, Characterization, and Crystal Structures of a Thiosemicarbazone Ligand and Its Silver(I) Complex [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
Thiosemicarbazone ligand 4Hbatsc = 4-hydroxybenzaldehyde-thiosemicarbazone and its silver(I) complex [Ag(PPh3)3(4Hbatsc)]NO3 were synthesized and characterized by elemental analysis (CHN), FT-IR spectroscopy, and single-crystal X-ray diffraction.
Ali Akbar Dehno Khalaji, Ensieh Shahsavani, Michal Dusek, Monika Kucerakova, Vaclav Eigner   +4 more
doaj   +1 more source

Unraveling the role of TP53 mutations in myeloproliferative neoplasms: Molecular mechanisms of leukemic transformation

HemaSphere, Volume 10, Issue 3, March 2026.
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito, Paula Sabbo Bernardo, Jean‐Edouard Martin, Caroline Marty, Isabelle Plo, Iléana Antony‐Debré, Bárbara da Costa Reis Monte‐Mór   +6 more
wiley   +1 more source

4-(Diphenylamino)benzaldehyde 4-phenylthiosemicarbazone

Acta Crystallographica Section E, 2012
The title molecule, C26H22N4S, is composed of three main parts, viz. a triphenylamine group is connected to a phenyl ring by a thiosemicarbazone moiety. The C= N double bond has an E conformation. The crystal packing is dominated by strong hydrogen bonds
Rafael Mendoza-Meroño, Laura Menéndez-Taboada, Santiago García-Granda   +2 more
doaj   +1 more source

Bis(4-methoxychalcone 4-ethylthiosemicarbazonato-κ2 N 1,S)zinc(II): Crystal structure and Hirshfeld surface analysis [PDF]

, 2018
The title ZnII complex, [Zn(C19H20N3OS)2] {systematic name: bis[(N-ethyl-N0-{(Z)-[(2E)-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-ylidene]amino}carbamimidoyl)sulfanido]zinc(II)}, features a tetrahedrally coordinated ZnII ion within an N2S2 donor set ...
Crouse, Karen A., Jotani, Mukesh M., Ravoof, Thahira Begum S. A., Tan, Ming Yueh, Tiekink, Edward R. T. *   +4 more
core   +1 more source

Polysaccharide‐Coated ETCA Nanoparticles Containing the Methoxyl Substituted Indole‐Thiazole Derivative and Their Antiproliferative Activity in Breast Cancer Cells

Journal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.
ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares, Iago Dillion Lima Cavalcanti, Iranildo José da Cruz‐Filho, Mariane Cajubá de Britto Lira Nogueira, Maria do Carmo Alves de Lima   +4 more
wiley   +1 more source

The Effect of the Serum Amino Acid Levels Thiosemicarbazone Derivatives and its Metal Complexes on Rats

Medicine Science, 2013
Advers biological activities of Thiosemicarbazone (TSC) and Schiff base (SB) derivatives have been widely studied in rats and in other animal species using different doses, times and routes of administration.
Mustafa Karatepe, Dilara Kaman
doaj   +1 more source

Half-sandwich arene ruthenium(II) and osmium(II) thiosemicarbazone complexes : solution behavior and antiproliferative activity [PDF]

, 2018
We report the synthesis, characterization and antiproliferative activity of organo-osmium(II) and organo-ruthenium(II) half-sandwich complexes [(η6-p-cym)Os(L)Cl]Cl (1 and 2) and [(η6-p-cym)Ru(L)Cl]Cl (3 and 4), where L = N-(2-hydroxy)-3 ...
Carcelli, Mauro, Clarkson, Guy J., Gatti, Anna, Habtemariam, Abraha, Heer, Bindy, Rogolino, Dominga, Romero-Canelón, Isolda, Sadler, P. J., Song, Ji-Inn   +8 more
core   +2 more sources

Synthesis, Characterization, Electrochemical Studies, and In Vitro Antibacterial Activity of Novel Thiosemicarbazone and Its Cu(II), Ni(II), and Co(II) Complexes

The Scientific World Journal, 2014
Metal complexes were prepared by the reaction of thiosemicarbazone with CuCl2, NiCl2, CoCl2, Cu(OAc)2, Ni(OAc)2, and Co(OAc)2. The thiosemicarbazone coordinates to metal through the thionic sulfur and the azomethine nitrogen.
Salman A. Khan, Abdullah M. Asiri, Khalid Al-Amry, Maqsood Ahmad Malik   +3 more
doaj   +1 more source

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li, Yibo He, Yang Zhang, Lining Arnold Ju, Yao Wang, Jianxuan Zhou, Yinying Chai, Xuhui Hui, ShiYuan Tong, Si Zhang, Yanli Tan, Yinyan Wang   +11 more
wiley   +1 more source