Results 21 to 30 of about 3,023 (198)

Identification and characterization of single‐domain thiosulfate sulfurtransferases from Arabidopsis thaliana [PDF]

FEBS Letters, 2002
Sulfurtransferases/rhodaneses (ST) are a group of enzymes widely distributed in all three phyla that catalyze the transfer of sulfur from a donor to a thiophilic acceptor substrate. All ST contain distinct structural domains, and can exist as single‐domain proteins, as tandemly repeated modules in which the C‐terminal domain bears the active site, or ...
Jutta Papenbrock, Michael Bauer
openaire   +4 more sources

Thiosulfate sulfurtransferase and UDP-glucuronosyltransferase activities in cholestatic rat liver induced by common bile duct ligation [PDF]

Experimental & Molecular Medicine, 1997
We have investigated the effect of cholestasis on the hepatic thiosulfate sulfurtransferase (rhodanese) and UDP-glucuronosyltransferase (UDP-GT) activities in rats. Rhodanese activities in the liver cytosol, mitochondria and microsomal fractions as well as in the rat serum, and UDP-GT activity in the microsome have been investigated for a period of 42 ...
Jong-Sool Ihm, You-Hee Kim
openaire   +4 more sources

Correction: Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness [PDF]

Nature Medicine, 2018
Nat. Med. 22, 771–779 (2016); published online 6 June 2016; corrected after print 7 March 2018 In the version of this article initially published, the colors of the lines were switched in the graph that shows the glucose infusion rates for wild-type mice and Adipoq-Tst transgenic mice in Figure 3b.
Petra Sipilä, Alexander F. Howie, Gregorio Naredo, Thomas M. Stulnig, Sergio Rodriguez-Cuenca, Aila Saari, Donald R. Dunbar, Christopher J. Kenyon, Roderick N. Carter, Zoi Michailidou, Clare McFadden, Simon Horvat, José Manuel Fernández-Real, Brian R. Walker, Maximilian Zeyda, Gary A. Churchill, Jasmina Beltram, Matthew T G Gibbins, Steven C. Munger, Jonathan R. Seckl, Vilmundur Gudnason, Martin E. Barrios-Llerena, Scott P. Webster, Annalisa Gastaldello, Gregor Gorjanc, Zhao V. Wang, Valur Emilsson, Karen L. Svenson, Rhona Aird, José María Moreno-Navarrete, Lynne Ramage, Antonio Vidal-Puig, Nicholas M. Morton   +32 more
openaire   +2 more sources

Hydrogen Sulfide Metabolizing Enzymes in the Intestinal Mucosa in Pediatric and Adult Inflammatory Bowel Disease. [PDF]

Antioxidants (Basel), 2022
Hydrogen sulfide (H2S) is a toxic gas that has important regulatory functions. In the colon, H2S can be produced and detoxified endogenously. Both too little and too much H2S exposure are associated with inflammatory bowel disease (IBD), a chronic ...
Stummer N, Weghuber D, Feichtinger RG, Huber S, Mayr JA, Kofler B, Neureiter D, Klieser E, Hochmann S, Lauth W, Schneider AM.   +10 more
europepmc   +2 more sources

Structural and functional characterization of sulfurtransferase from Frondihabitans sp. PAMC28461. [PDF]

PLoS One
Sulfurtransferases transfer of sulfur atoms from thiols to acceptors like cyanide. They are categorized as thiosulfate sulfurtransferases (TSTs) and 3-mercaptopyruvate sulfurtransferases (MSTs). TSTs transfer sulfur from thiosulfate to cyanide, producing
Do H, Nguyen DL, Ahn YY, Nam Y, Kang Y, Oh H, Hwang J, Han SJ, Kim K, Lee JH.   +9 more
europepmc   +2 more sources

Bridging the Gap in Cancer Research: Sulfur Metabolism of Leukemic Cells with a Focus on L-Cysteine Metabolism and Hydrogen Sulfide-Producing Enzymes. [PDF]

Biomolecules
Leukemias are cancers of the blood-forming system, representing a significant challenge in medical science. The development of leukemia cells involves substantial disturbances within the cellular machinery, offering hope in the search for effective ...
Kaleta K, Janik K, Rydz L, Wróbel M, Jurkowska H.   +4 more
europepmc   +2 more sources

Thiosulphate sulfurtransferase: Biological roles and therapeutic potential. [PDF]

Redox Biol
Mitochondria are central to eukaryotic cell function, driving energy production, intermediary metabolism, and cellular homeostasis. Dysregulation of mitochondrial function often results in oxidative stress, a hallmark of numerous diseases, underscoring ...
Luo Y, Melhem S, Feelisch M, Chatre L, Morton NM, Dolga AM, van Goor H.   +6 more
europepmc   +2 more sources

Involvement of the Azotobacter vinelandii Rhodanese-Like Protein RhdA in the Glutathione Regeneration Pathway [PDF]

, 2012
The phenotypic features of the Azotobacter vinelandii RhdA mutant MV474 (in which the rhdA gene was deleted) indicated that defects in antioxidant systems in this organism were related to the expression of the tandem-domain rhodanese RhdA.
Forlani, Fabio, Guerrieri, Nicoletta, Klodmann, Jennifer, Pagani, Silvia, Papenbrock, Jutta, Remelli, William   +5 more
core   +11 more sources

Sulfurtransferases and Cystathionine Beta-Synthase Expression in Different Human Leukemia Cell Lines

Biomolecules, 2022
The studies concerned the expression of sulfurtransferases and cystathionine beta-synthase in six human leukemia cell lines: B cell acute lymphoblastic leukemia-B-ALL (REH cells), T cell acute lymphoblastic leukemia-T-ALL (DND-41 and MOLT-4 cells), acute
Halina Jurkowska, Maria Wróbel, Ewa Jasek-Gajda, Leszek Rydz   +3 more
doaj   +1 more source

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, EarlyView., 2023
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source