Results 51 to 60 of about 1,815 (145)

Transcription factor YcjW controls the emergency H2S production in E. coli

Nature Communications, 2019
Hydrogen sulfide (H2S) production in Escherichia coli is controlled by the sulfurtransferase 3MST. Here, the authors describe an alternative mechanism for H2S biosynthesis via activation of the thiosulfate sulfurtransferase PspE, a process mediated by ...
Lyly Luhachack, Aviram Rasouly, Ilya Shamovsky, Evgeny Nudler   +3 more
doaj   +1 more source

H₂S, Polysulfides, and Enzymes: Physiological and Pathological Aspects

Biomolecules, 2020
We have been studying the general aspects of the functions of H2S and polysulfides, and the enzymes involved in their biosynthesis, for more than 20 years.
Noriyuki Nagahara, Maria Wróbel
doaj   +1 more source

Promoter hypomethylation and overexpression of TSTD1 mediate poor treatment response in breast cancer

Frontiers in Oncology, 2022
Epigenetic alterations play a pivotal role in cancer treatment outcomes. Using the methylation array data and The Cancer Genome Atlas (TCGA) dataset, we observed the hypomethylation and upregulation of thiosulfate sulfurtransferase–like domain containing
Muhamad Ansar, Le Thi Anh Thu, Le Thi Anh Thu, Chin-Sheng Hung, Chin-Sheng Hung, Chin-Sheng Hung, Chih-Ming Su, Chih-Ming Su, Man-Hsu Huang, Li-Min Liao, Yu-Mei Chung, Ruo-Kai Lin, Ruo-Kai Lin, Ruo-Kai Lin, Ruo-Kai Lin   +14 more
doaj   +1 more source

Metabolic and vascular effects of thiosulfate sulfurtransferase deletion

, 2018
Hydrogen sulfide (H2S), is a gasotransmitter with several key roles in metabolism and vascular function. The effects of H2S are dependent on concentration and target organ. For example, increased H2S concentrations impair liver metabolic function but protect against vascular dysfunction and atherosclerosis.
Matthew Thomas George Gibbins
openalex   +2 more sources

Hydrogen sulfide as an anti-calcification stratagem in human aortic valve: Altered biogenesis and mitochondrial metabolism of H2S lead to H2S deficiency in calcific aortic valve disease

Redox Biology, 2023
Hydrogen sulfide (H2S) was previously revealed to inhibit osteoblastic differentiation of valvular interstitial cells (VICs), a pathological feature in calcific aortic valve disease (CAVD).
Zsolt Combi, László Potor, Péter Nagy, Katalin Éva Sikura, Tamás Ditrói, Eszter Petra Jurányi, Klaudia Galambos, Tamás Szerafin, Péter Gergely, Matthew Whiteman, Roberta Torregrossa, Yuchao Ding, Lívia Beke, Zoltán Hendrik, Gábor Méhes, György Balla, József Balla   +16 more
doaj   +1 more source

Identification and characterization of single‐domain thiosulfate sulfurtransferases from Arabidopsis thaliana [PDF]

FEBS Letters, 2002
Sulfurtransferases/rhodaneses (ST) are a group of enzymes widely distributed in all three phyla that catalyze the transfer of sulfur from a donor to a thiophilic acceptor substrate. All ST contain distinct structural domains, and can exist as single‐domain proteins, as tandemly repeated modules in which the C‐terminal domain bears the active site, or ...
Bauer, Michael, Papenbrock, Jutta
openaire   +2 more sources

Feeding low or pharmacological concentrations of zinc oxide changes the hepatic proteome profiles in weaned piglets. [PDF]

PLoS ONE, 2013
Pharmacological levels of zinc oxide can promote growth and health of weaning piglets, but the underlying molecular mechanisms are yet not fully understood.
Angelika Bondzio, Robert Pieper, Christoph Gabler, Christoph Weise, Petra Schulze, Juergen Zentek, Ralf Einspanier   +6 more
doaj   +1 more source

Hydrogen Sulfide Prevents Mesenteric Adipose Tissue Damage, Endothelial Dysfunction, and Redox Imbalance From High Fructose Diet-Induced Injury in Aged Rats

Frontiers in Pharmacology, 2021
A high fructose diet (HFD) and advanced age are key factors for the gradual loss of physiological integrity of adipose tissue. Endogenous hydrogen sulfide (H2S) has beneficial effects on cytoprotection and redox balance.
Oleh Revenko, Yaroslav Pavlovskiy, Maryana Savytska, Antonina Yashchenko, Vasyl Kovalyshyn, Ilona Chelpanova, Olena Varyvoda, Oksana Zayachkivska   +7 more
doaj   +1 more source

H2S Donors Reverse Age-Related Gastric Malfunction Impaired Due to Fructose-Induced Injury via CBS, CSE, and TST Expression

Frontiers in Pharmacology, 2020
ObjectiveExcess of fructose consumption is related to life-treating conditions that affected more than a third of the global population. Therefore, to identify a newer therapeutic strategy for the impact prevention of high fructose injury in age-related ...
Yaroslav Pavlovskiy, Antonina Yashchenko, Oksana Zayachkivska   +2 more
doaj   +1 more source

Full-Length Transcriptome Comparison Provides Novel Insights into the Molecular Basis of Adaptation to Different Ecological Niches of the Deep-Sea Hydrothermal Vent in Alvinocaridid Shrimps

Diversity, 2022
The deep-sea hydrothermal vent ecosystem is one of the extreme chemoautotrophic environments. Shinkaicaris leurokolos Kikuchi and Hashimoto, 2000, and Alvinocaris longirostris Kikuchi and Ohta, 1995, are typically co-distributed and closely related ...
Aiyang Wang, Zhongli Sha, Min Hui
doaj   +1 more source