Results 11 to 20 of about 5,865 (290)

Continuous-Flow Synthesis of Thioureas, Enabled by Aqueous Polysulfide Solution

Molecules, 2021
We have developed the continuous-flow synthesis of thioureas in a multicomponent reaction starting from isocyanides, amidines, or amines and sulfur. The aqueous polysulfide solution enabled the application of sulfur under homogeneous and mild conditions.
András Gy. Németh, Renáta Szabó, György Orsy, István M. Mándity, György M. Keserű, Péter Ábrányi-Balogh   +5 more
doaj   +2 more sources

A New Class of Glucosyl Thioureas: Synthesis and Larvicidal Activities

Molecules, 2016
A novel series of glucosyl thioureas were synthesized in good overall yields (up to 37% over four steps) from d-glucose and primary amines, and their larvicidal activities toward Mythimna separata Walker were also investigated. This new class of glucosyl
Ping-An Wang, Jun-Tao Feng, Xing-Zi Wang, Mu-Qiong Li   +3 more
doaj   +2 more sources

Synthesis of N-(Methoxycarbonylthienylmethyl)thioureas and Evaluation of Their Interaction with Inducible and Neuronal Nitric Oxide Synthase

Molecules, 2010
Two isomeric N-(methoxycarbonylthienylmethyl)thioureas were synthesised by a sequence of radical bromination of methylthiophenecarboxylic esters, substitution with trifluoroacetamide anion, deprotection, formation of the corresponding isothiocyanates and
Michael D. Threadgill, Claire L.M. Goodyer, Ghadeer A.R.Y. Suaifan   +2 more
doaj   +3 more sources

Synthesis of Peracetylated β-D-Glucopyranosyl Thioureas from Substituted 2-Aminobenzo-1ʹ, 3ʹ-thiazoles [PDF]

E-Journal of Chemistry, 2012
Some peracetylated glucopyranosyl thioureas containing a heterocyclic ring system, benzo-1,3-thiazole have been prepared by the condensation reaction of tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate and corresponding substituted 2-amino-(6-substituted)
Nguyen Dinh Thanh
doaj   +2 more sources

Synthesis and Antitumor Activities of Chiral Dipeptide Thioureas Containing an Alpha-Aminophosphonate Moiety

Molecules, 2017
Thiourea derivatives demonstrate potent cytotoxic activity against various leukemias and many tumor cell lines. In our previous study, the combination of thiourea and phosphonate has been proven as an effective strategy for developing antitumor agents ...
Jingzi Liu, Peng Liao, Junfeng Hu, Hong Zhu, Yonglin Wang, Yongjun Li, Yan Li, Bin He   +7 more
doaj   +2 more sources

Synthesis and Crystal Structure of 1-(3-fluorophenyl)-3-(3,4,5-trimethoxybenzoyl)thiourea [PDF]

, 2011
The title thiourea was synthesized by reaction of 3,4,5-trimethoxybenzoyl isothiocyante with 3-fluoroaniline. The 3,4,5-trimethoxybenzoyl isothiocyante was produced in situ by reaction of 3,4,5-trimethoxybenzoyl chloride with ammonium thiocyanate in dry ...
Bolte, Michael, Michael Bolte, Shaheen, Uzma, Uzma Shaheen, Saeed, Aamer, Aamer Saeed   +5 more
core   +1 more source

Adamantyl thioureas as soluble epoxide hydrolase inhibitors [PDF]

, 2018
A series of inhibitors of the soluble epoxide hydrolase (sEH) containing one or two thiourea groups has been developed. Inhibition potency of the described compounds ranges from 50 μM to 7.2 nM.
Dmitry Karlov, Hammock, Bruce D, Butov, Gennady M, Gennady M. Butov, Karlov, Dmitry, Burmistrov, Vladimir, Fayzullin, Robert R, Morisseau, Christophe, Vladimir Burmistrov, Robert R. Fayzullin, Bruce D. Hammock, Christophe Morisseau, Dmitry Pitushkin, Pitushkin, Dmitry   +13 more
core   +1 more source

Hydrogen-Bonding Interactions in Crystalline Solids of Cyclic Thioureas

, 2016
The crystal structures of three cyclic thioureas (4,5-disubstituted benzimidazolene-2-thiones) are reported. Each compound forms a tape motif in the solid state. Two of the three compounds assemble into tapes via N−H- - -S hydrogen bonds.
Mary T. McBride (352828), Tzy-Jiun M. Luo (2038327), G. Tayhas R. Palmore (1753864)   +2 more
core   +3 more sources

One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyanophenyl) benzimidoyl isothiocyanate

Molecules, 2001
1-substituted-3-(2-phenylquinazolin-4-yl) thioureas (7) were produced by an intramolecular cycloaddition reaction of 1-substitued-3-[(2-cyanophenylimino) phenylmethyl] thioureas (3).
P. Pazdera, J. Marek, M. Čajan, W. Fathalla   +3 more
doaj   +1 more source

Secondary amine-initiated three-component synthesis of 3,4-dihydropyrimidinones and thiones involving alkynes, aldehydes and thiourea/urea

Beilstein Journal of Organic Chemistry, 2014
The three-component reactions of aldehydes, electron deficient alkynes and ureas/thioureas have been smoothly performed to yield a class of unprecedented 3,4-dihydropyrimidinones and thiones (DHPMs).
Jie-Ping Wan, Yunfang Lin, Kaikai Hu, Yunyun Liu   +3 more
doaj   +1 more source