Results 291 to 300 of about 884,760 (321)

MinimapR: A parallel alignment tool for the analysis of large-scale third-generation sequencing data

Comput. Biol. Chem., 2022
The development of third-generation sequencing technology has brought significant changes and influences on genomics. Compared to the second-generation sequencing methods, the third-generation technologies produce around 100 times longer reads to reveal ...
Zihang Wang, Yingbo Cui, Shaoliang Peng, Xiangke Liao, Yang Yu   +4 more
semanticscholar   +1 more source

Enhancing Thalassemia Diagnosis: Advantages of Third-Generation Sequencing

Clinical Laboratory
This study aimed to evaluate the efficacy of third-generation sequencing (TGS) and a thalassemia (Thal) gene diagnostic kit in identifying Thal gene mutations.Blood samples (n = 119) with positive hematology screening results were tested using polymerase chain reaction (PCR)-based methods and TGS on the PacBio-Sequel-II-platform, respectively.Out of ...
Minjun, Huang, Jiexiang, Huang, Liumin, Yu, Kun, Lin   +3 more
openaire   +2 more sources

Third Generation DNA Sequencing with a Nanopore

2011
With the advent of Next-Generation-Sequencing (NGS) technologies, an enormous volume of DNA sequencing data can be generated at low cost, placing genomic science within the grasp of everyday medicine. However, mired in this voluminous data, a new problem has emerged: the assembly of the genome from the short reads.
Gregory Timp, Utkur Mirsaidov, Winston Timp, Jiwook Shim, Deqiang Wang, Valentin Dimitrov, Jan Scrimgeour, Chunchen Lin, Jeffrey Comer, Anthony H. Ho, Xueqing Zou, Aleksei Aksimentiev, Klaus Schulten   +12 more
openaire   +1 more source

Comparing the Accuracy and Efficiency of Third Generation Sequencing Technologies, Oxford Nanopore Technologies, and Pacific Biosciences, for DNA Barcode Sequencing Applications

Social Science Research Network, 2023
P. Cuber, D. Chooneea, Clementine Geeves, S. Salatino, Thomas J. Creedy, C. Griffin, Laura Sivess, Ian Barnes, Ben Price, Raju Misra   +9 more
semanticscholar   +1 more source

Next-Generation and Third-Generation Sequencing of Lung Cancer Biomarkers

2017
In lung cancer, biomarker-guided therapy selection has greatly improved patient outcome. The recent introduction of next-generation sequencing (NGS) technology has rapidly expanded our understanding of disease-driving gene mutations and resulted in identification of key lung cancer biomarkers.
openaire   +1 more source

Interventional gastroenterology in oncology

Ca-A Cancer Journal for Clinicians, 2023
Vaibhav Wadhwa
exaly  

Third-generation sequencing fireworks at Marco Island

Nature Biotechnology, 2010
David J Munroe, Timothy J R Harris
openaire   +1 more source

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel, William K Oh, Matthew D Galsky   +2 more
exaly  

[Research progress and clinical application of the third- generation sequencing techniques].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2022
D. Tan, Tong Ou
semanticscholar   +1 more source

Treatment of renal cell carcinoma: Current status and future directions

Ca-A Cancer Journal for Clinicians, 2017
Pedro Coelho Barata, Brian I Rini
exaly