Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research [PDF]
Frontiers in Oncology, 2022 Replicating the naturalistic biomechanical milieu of cells is a primary requisite to uncover the fundamental life processes. The native milieu is significantly not replicated in the two-dimensional (2D) cell cultures.
Kolluri Poornima +11 more
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Three-dimensional cell culture for the study of nasal polyps [PDF]
Brazilian Journal of Otorhinolaryngology, 2022 Objectives: Three-dimensional (3D) cell cultures have many applications such as stem cell biology research, new drug discovery, cancer, and Chronic Rhinosinusitis with Nasal Polyps (CRSwNP).
Carolina Nunes França +5 more
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Role of three-dimensional cell culture in therapeutics and diagnostics: an updated review. [PDF]
Drug Deliv Transl Res, 2023 Drug development and testing are a tedious and expensive process with a high degree of uncertainty in the clinical success and preclinical validation of manufactured therapeutic agents.
Biju TS, Priya VV, Francis AP.
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Current strategies with implementation of three-dimensional cell culture: the challenge of quantification. [PDF]
Interface Focus, 2022 From growing cells in spheroids to arranging them on complex engineered scaffolds, three-dimensional cell culture protocols are rapidly expanding and diversifying.
Temple J, Velliou E, Shehata M, Lévy R.
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Biomaterials for Three-Dimensional Cell Culture: From Applications in Oncology to Nanotechnology. [PDF]
Nanomaterials (Basel), 2021 Three-dimensional cell culture has revolutionized cellular biology research and opened the door to novel discoveries in terms of cellular behavior and response to microenvironment stimuli.
Saydé T +5 more
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Three-Dimensional Cell Culture Methods in Infectious Diseases and Vaccine Research
Future Pharmacology, 2023 Cells, the basic structures of all living organisms, reside in an extracellular matrix consisting of a complex three-dimensional architecture and interact with neighboring cells both mechanically and biochemically. Cell–cell and cell–extracellular matrix
Gamze Varan, Serhat Unal
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Biomimetic Scaffolds-A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering. [PDF]
Nanomaterials (Basel)Biomimetic scaffolds imitate native tissue and can take a multidimensional form. They are biocompatible and can influence cellular metabolism, making them attractive bioengineering platforms. The use of biomimetic scaffolds adds complexity to traditional
Górnicki T +14 more
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Electrostatic Patterning of Nanofibrous Microcapsules for Three-Dimensional Cell Culture [PDF]
Journal of Functional BiomaterialsThree-dimensional biomaterial scaffolds with controlled geometry and surface nanoarchitecture are essential for advancing polymer processing strategies in tissue engineering.
Masashi Ikeuchi +6 more
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A Novel Hydrogel Sponge for Three-Dimensional Cell Culture [PDF]
PharmaceuticsBackground/Objectives: Three-dimensional (3D) cell culture technologies allow us to overcome the constraints of two-dimensional methods in different fields like biochemistry and cell biology and in pharmaceutical in vitro tests. In this study, a novel 3D
Sara Baldassari +10 more
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Three-Dimensional Cell Culture Systems for Studying Hepatitis C Virus [PDF]
Viruses, 2021 Hepatocytes, the major target of hepatitis C virus (HCV), are highly polarized. HCV infection requires extensive trafficking to distinct subcellular domains in the polarized hepatocyte. Polarized cells and three-dimensional organoids are commonly used to
Chui-Wa So, Glenn Randall
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