Three-dimensional cell culture technique and pathophysiology [PDF]
Three-dimensional (3D) tissue constructs consisting of human cells have opened a new avenue for tissue engineering, pharmaceutical and pathophysiological applications, and have great potential to estimate the dynamic pharmacological effects of drug candidates, metastasis processes of cancer cells, and toxicity expression of nano-materials, as a 3D ...
Michiya, Matsusaki +2 more
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Microfluidic Invasion Chemotaxis Platform for 3D Neurovascular Co-Culture
Advances in microfabrication and biomaterials have enabled the development of microfluidic chips for studying tissue and organ models. While these platforms have been developed primarily for modeling human diseases, they are also used to uncover cellular
Emel Sokullu +5 more
doaj +1 more source
From crypts to enteroids: establishment and characterization of avian intestinal organoids
: Intestinal organoids (IO), known as “mini-guts”, derived from intestinal crypts, are self-organizing three-dimensional (3D) multicellular ex vivo models that recapitulate intestine epithelial structure and function and have been widely used for ...
Dan Zhao +7 more
doaj +1 more source
Advances in Stem Cell Therapy Based on Tissue Engineering in the Treatment of Female Infertility with a Focus on POF [PDF]
Background: In the last few decades, many studies have been done on the treatment of premature ovarian failure. This review was conducted to study different types of treatment with a focus on the 3D culture model of stem cells as a pluripotent source for
Shadan Navid +5 more
doaj +1 more source
QUANTITATIVE REPRESENTATION OF THREE-DIMENSIONAL CELL CULTURE MODELS [PDF]
Three-dimensional mammary cell culture models offer new opportunities for the development of computational techniques for segmentation, localization, and multicellular organization. Under normal conditions, these assays form a symmetrical, hollow structure, which is necessary for their functional operation.
Chang, Hang +2 more
openaire +2 more sources
Three-dimensional cell culture: from evolution to revolution [PDF]
Recent advances in the isolation of tissue-resident adult stem cells and the identification of inductive factors that efficiently direct differentiation of human pluripotent stem cells along specific lineages have facilitated the development of high-fidelity modelling of several tissues in vitro
Sharmin Alhaque +2 more
openaire +4 more sources
Preparation of a three-dimensional full thickness skin equivalent
S.191-198In vitro test systems are a promising alternative to animal models. Due to the use of human cells in a three-dimensional arrangement that allows cell-cell or cell-matrix interactions these models may be more predictive for the human situation ...
Walles, Heike +2 more
core +1 more source
Mimicking Epithelial Tissues in Three-Dimensional Cell Culture Models
Epithelial tissues are composed of layers of tightly connected cells shaped into complex three-dimensional (3D) structures such as cysts, tubules, or invaginations.
Núria Torras +5 more
doaj +1 more source
Three-dimensional cell culture
The present invention relates to a three-dimensional cell culture system for culturing adipocytes. The invention also relates to methods for culturing adipocytes and for obtaining adipocytes from preadipocytes in cell culture.
Loughlin, Jane +2 more
core +3 more sources
Tuning the structure and properties of cell-embedded gelatin hydrogels for tumor organoids [PDF]
Tumor organoids have great potential as a 3D in vitro system to model cancer. In this work, we studied how the structure of hydrogels based on gelatin with methacryloyl groups (GeIMA) can affect their usage in tumor organoids.
Sarah Oliveira Lamas de Souza +5 more
doaj +1 more source

