Results 191 to 200 of about 20,905,469 (291)

Advanced Three-Dimensional Cell Culture Models for Investigating Enterohaemorrhagic <i>Escherichia coli</i> Pathogenesis and Shiga Toxin-Mediated Injury. [PDF]

J Microbiol Biotechnol
Park SH, Kim M, Jeong YJ, Lee MS.
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Chrysin induces cell death and inhibits migration and invasion in squamous cervical carcinoma using a three-dimensional cell culture model. [PDF]

Braz J Med Biol Res
Mari NL, Souza MVF, Meirelles LEF, Carvalho ARBA, Shinobu-Mesquita CS, Bruschi ML, Consolaro MEL, Silva VRSD.   +7 more
europepmc   +1 more source

Effects of Gallic Acid on Endometrial Cancer Cells in Two and Three Dimensional Cell Culture Models. [PDF]

Asian Pac J Cancer Prev, 2021
Bulbul MV, Karabulut S, Kalender M, Keskin I.   +3 more
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Targeted genome editing of ZKSCAN3 mitigates the neurotoxicity caused by mutant HTT (huntingtin) in a Huntington disease animal model and three-dimensional cell culture of Huntington disease. [PDF]

Autophagy
Park HJ, Kim J, Choi J, Ryou C, Shin E, Lee JY.   +5 more
europepmc   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Synthetic Extracellular Matrix of Polyvinyl Alcohol Nanofibers for Three-Dimensional Cell Culture. [PDF]

J Funct Biomater
Tran TXT, Sun GM, Tran HVA, Jeong YH, Slama P, Chang YC, Lee IJ, Kwak JY.   +7 more
europepmc   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Bone Graft Paste Nanohydroxyapatite Chitosan-Gelatin (nHA/KG) for Periodontal Regeneration: Study on Three-Dimensional Cell Culture. [PDF]

Eur J Dent
Harsas NA, Bachtiar EW, Amir LR, Mauludin R, Sunarso S, Yosefa V, Savvyana M, Tadjoedin FM, Soeroso Y.   +8 more
europepmc   +1 more source