Results 231 to 240 of about 18,631,052 (336)

The Role of Viscoelasticity in Heterogeneous Glioblastoma Stem Cell Invasion in Biomimetic 3‐Dimensional Hydrogels

Advanced Healthcare Materials, EarlyView.
The role of viscoelasticity in the invasion of heterogeneous glioblastoma stem cells (GSCs) was investigated with GSCs categorized into subgroups based on molecular profile, as Reactive, Invasive, or Constructive using viscoelastic biomimetic hyaluronan‐oxime hydrogels.
Nicole J. Blaine, Arianna Skirzynska, Allysia A. Chin, Julie Audet, Molly S. Shoichet   +4 more
wiley   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

RGD peptide promotes follicle growth through integrins αvβ3/αvβ5 in three-dimensional culture. [PDF]

Reproduction
Matsushige C, Kitazumi K, Beaman A, Miyagi M, Tallquist MD, Yamazaki Y.   +5 more
europepmc   +1 more source

Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes

Development, 2013
S. Ogawa, James Surapisitchat, C. Virtanen, Mina Ogawa, M. Niapour, K. Sugamori, Shuang Wang, L. Tamblyn, C. Guillemette, E. Hoffmann, Bin Zhao, S. Strom, R. Laposa, R. Tyndale, D. Grant, G. Keller   +15 more
semanticscholar   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Atelocollagen supports three-dimensional culture of human induced pluripotent stem cells. [PDF]

Mol Ther Methods Clin Dev
Nakashima Y, Tsukahara M.
europepmc   +1 more source

Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition

Cell Cycle, 2013
Michael Amatangelo, Azat Garipov, Hua Li, J. Conejo-Garcia, D. Speicher, Ru-Gang Zhang   +5 more
semanticscholar   +1 more source

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

Advanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu, Xinggui Tian, Anne Bernhardt, Anja Lode, Max von Witzleben, Ege Kirbas, Stefan Zwingenberger, Michael Gelinsky   +7 more
wiley   +1 more source

Establishment of an experimental model of canine apocrine gland anal sac adenocarcinoma organoid culture using a three-dimensional culture method. [PDF]

Sci Rep
Nagashima Y, Yamamoto H, Elbadawy M, Ishihara Y, Tsurukami I, Abugomaa A, Kaneda M, Yamawaki H, Usui T, Sasaki K.   +9 more
europepmc   +1 more source

Magnetoactive Hydrogels to Probe Curvature‐Directed Endothelial Cell Mechanosensing

Advanced Healthcare Materials, EarlyView.
This work establishes a platform to investigate local curvature as a regulator of endothelial mechanosensing independent of shear stress. Magnetoactive hydrogels enable on‐demand curvature of endothelial monolayers to reproduce tortuosity quantified by clinically established metrics.
Avinava Roy, Grace K. Hinds, Joshua Yu‐Chung Liu, Ziqian Yang, Rishab Yanala, Arina E. Velieva, Claudia Loebel   +6 more
wiley   +1 more source