Results 131 to 140 of about 611,533 (383)
Advanced Healthcare Materials, EarlyView.This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement +12 more
wiley +1 more source
Activation of type II calcium/calmodulin-dependent protein kinase by Ca^(2+)/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain [PDF]
, 1990 It is now well established that autophosphorylation of a threonine residue located next to each calmodulin-binding domain in the subunits of type II Ca^(2+)/calmodulin-dependent protein kinase causes the kinase to remain active, although at a reduced ...
Kennedy, Mary B. +2 more
core
Advanced Therapeutics, EarlyView.This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack +13 more
wiley +1 more source
Effects of different dietary threonine levels on growth and slaughter performance in finishing pigs
Czech Journal of Animal Science, 2007 The objective of this study was to determine the threonine (Thr) requirement of a modern crossbred growing pig from Austria in the finisher stage (67 to 113 kg body weight).
C. Plitzner +4 more
doaj +1 more source
Calcium-cadmium interaction on L-threonine intestinal transport [PDF]
, 1995 José Emilio Mesonero +2 more
openalex +1 more source
Faba beans in diets for growing-finishing pigs [PDF]
, 2003 Two experiments were carried out to study the effects of using the new faba bean (Vicia faba L.) cultivar Kontu as a domestic protein source for growing-finishing pigs.In Experiment 1,120 pigs were used with a body weight (BW)of 25–110 kg to study the ...
Alaviuhkola, Timo +3 more
core
Advanced Science, EarlyView.YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang +8 more
wiley +1 more source
Frontiers in Animal ScienceBroiler chickens are economically, nutritionally, and culturally very important. An experiment was conducted to determine the effect of dietary threonine level on the growth performance of slow-growing 50- to 91-day-old male Boschveld chickens.
Tebogo Mack Sekgotodi +2 more
doaj +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Supplementing low protein diets with methionine or threonine during mixed Eimeria challenge
Poultry Science: We investigated the effects of supplementing low protein diets with methionine (Met) or threonine (Thr) during a mixed Eimeria (consisting of E. acervulina, E. maxima and E. tenella) challenge in broilers. All birds were fed the same starter diet (d1–9)
James Taylor +8 more
doaj +1 more source