Results 131 to 140 of about 3,607,125 (302)
threshold-effect concentration
Citation: 'threshold-effect concentration' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15093 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Can asymmetries account for the empirical failure of the Fisher effect in South Africa? [PDF]
This paper investigates whether unobserved asymmetries can account for irregularities in the Fisher effect for the exclusive case of South Africa. This objective is attained by investigating unit roots within a threshold auto-regressive (TAR) models and ...
Andrew Phiri, Peter Lusanga
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
EVIDÊNCIAS EMPÍRICAS SOBRE CONVERGÊNCIA DA DESIGUALDADE DE RENDA ENTRE OS MUNICÍPIOS CEARENSES
Revista de Políticas Públicas, 2014 The income inequality tends to decrease in municipalities with high inequality and increase in those with low inequality? This paper intends to answer this question by checking if there was convergence of income inequality in the municipalities of the ...
Airton Lopes Amorim +3 more
doaj
FoodsTea trees (Camellia sinensis) growing on selenium (Se)-rich soils often exhibit the phenomenon of cadmium (Cd) accumulation. However, the transport of Cd in the soil–tea tree–tea infusion continuum in such areas, as well as the impact of Se on Cd in this
Haizhong Wu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The threshold effect of the Taiwan stock market on ETF under the monetary policy
Technological and Economic Development of EconomyTaiwan’s central bank produces tightening or easing effects by controlling the rediscount rate, which indirectly affects the stock market. An exchange-traded fund (ETF) is a fund that tracks the stock market index.
Tzu-Yi Yang
doaj +1 more source