Results 71 to 80 of about 3,798,889 (297)

The Lasso for High-Dimensional Regression with a Possible Change-Point [PDF]

, 2014
We consider a high-dimensional regression model with a possible change-point due to a covariate threshold and develop the Lasso estimator of regression coefficients as well as the threshold parameter.
Lee, Sokbae, Seo, Myung Hwan, Shin, Youngki   +2 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessing the Influence of Environmental Factors on Landslide Frequency and Intensity in Northwestern Sichuan, SW China, Using Multi-Temporal Satellite Imagery

Remote Sensing
Landslides are a significant geological hazard with substantial socio-economic and environmental consequences, particularly in northwestern Sichuan, SW China, where complex geological and climatic conditions contribute to their occurrence.
Yu Zhu, Huajin Li, Ran Tang, Zhanfeng Fan, Lixuan Mao, Yifei Lu, Chuanhao Pu, Yusen He   +7 more
doaj   +1 more source

A simulation study for the analysis of uncertain binary responses: Application to first insemination success in beef cattle

Genetics Selection Evolution, 2005
A simulation was carried out to investigate the methods of analyzing uncertain binary responses for success or failure at first insemination. A linear mixed model that included, herd, year, and month of mating as fixed effects; and unrelated service sire,
Rekaya Romdhane, Spangler Matthew L, Sapp Robyn L, Bertrand J Keith   +3 more
doaj   +1 more source

Model-Robust Inference for Continuous Threshold Regression Models [PDF]

Biometrics, 2016
Summary We study threshold regression models that allow the relationship between the outcome and a covariate of interest to change across a threshold value in the covariate. In particular, we focus on continuous threshold models, which experience no jump at the threshold.
Fong, Youyi, Di, Chongzhi, Huang, Ying, Gilbert, Peter B.   +3 more
openaire   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Sustainable digital transformation: the nexus between ICT and global green economic growth

Technological and Economic Development of Economy
As a new engine to promote global economic and social development, information and communication technology (ICT) plays a key role in the field of modern economy.
Yiwen Li, Xia Li, Xiaojuan Wang, Chao Feng   +3 more
doaj   +1 more source

Exploration of lagged relationships between mastitis and milk yield in dairycows using a Bayesian structural equation Gaussian-threshold model

Genetics Selection Evolution, 2008
A Gaussian-threshold model is described under the general framework of structural equation models for inferring simultaneous and recursive relationships between binary and Gaussian characters, and estimating genetic parameters.
Gianola Daniel, Heringstad Bjørg, Wu Xiao-Lin   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

How economic high-quality development affects entrepreneurial efficiency promotions? A multilevel analysis

Cogent Business & Management
Entrepreneurial efficiency (EE) promotion is an important component of urban governance, but how high-quality economic development can affect EE has not been deeply discussed. Based on the cross-sectional data of business incubators in 287 Chinese cities,
Jinlin Cheng, Mingzhe Wu, Baoping Liu, Wei Luo, Huan Wang   +4 more
doaj   +1 more source