Results 71 to 80 of about 1,945,580 (301)

Pulse stretcher for narrow pulses [PDF]

open access: yes, 1973
Pulse stretching circuit can linearly stretch pulses as narrow as 50 nanoseconds and block incoming pulses following accepted input pulse until processing has been completed.
Lindsey, R. S., Jr.
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Who is more susceptible to job stressors and resources? Sensory-processing sensitivity as a personal resource and vulnerability factor.

open access: yesPLoS ONE, 2019
This study aimed to investigate whether people scoring higher (compared to lower) on sensory-processing sensitivity respond differently to the work environment.
Tinne Vander Elst   +5 more
doaj   +1 more source

Broadcasting on Random Directed Acyclic Graphs

open access: yes, 2020
We study a generalization of the well-known model of broadcasting on trees. Consider a directed acyclic graph (DAG) with a unique source vertex $X$, and suppose all other vertices have indegree $d\geq 2$.
Makur, Anuran   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial. [PDF]

open access: yesPLoS ONE, 2012
Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disease changes in central pain processing, e.g. central sensitization manifest as spreading hyperalgesia, can result from ongoing nociceptive input.
Stefan A W Bouwense   +5 more
doaj   +1 more source

Dynamics and sparsity in latent threshold factor models: A study in multivariate EEG signal processing

open access: yes, 2016
We discuss Bayesian analysis of multivariate time series with dynamic factor models that exploit time-adaptive sparsity in model parametrizations via the latent threshold approach.
Nakajima, Jouchi, West, Mike
core   +1 more source

Dogs are not better than humans at detecting coherent motion [PDF]

open access: yes, 2017
The ability to perceive motion is one of the main properties of the visual system. Sensitivity in detecting coherent motion has been thoroughly investigated in humans, where thresholds for motion detection are well below 10% of coherence, i.e.
Battaglini, Luca   +4 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy