Results 101 to 110 of about 249,410 (353)

Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors [PDF]

Aptamer functionalized addressable SWNT-film arrays between cantilever electrodes were successfully developed for biosensor applications. Dielectrophoretically aligned SWNT suspended films made possible highly specific and rapid detection of target ...
An, T, HAHN, SEI KWANG, Kim, KS, Lim, G
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Comparative Investigation of Thromboelastometry and Thrombin Generation for Patients Receiving Direct Oral Anticoagulants or Vitamin K Antagonists

Diagnostics
Background. Alterations induced by direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs) to thromboelastometry and thrombin generation are not well defined.
Armando Tripodi, Marco Capecchi, Erica Scalambrino, Marigrazia Clerici, Barbara Scimeca, Pasquale Agosti, Paolo Bucciarelli, Andrea Artoni, Flora Peyvandi   +8 more
doaj   +1 more source

The Modified Recombinant Proinsulin: A Simple and Efficient Way to Produce Insulin Glargine in E. coli

Research in Molecular Medicine, 2021
Background: Recombinant insulin glargine, a long-acting analog of insulin, is expressed as proinsulin in the host cell and, after purification and refolding steps, is processed to mature insulin by using trypsin and carboxypeptidase B. Because of several
Seyyedeh khadijeh Hosseini oula, Ali Reza Saeedinia, Mehdi Zeinoddini   +2 more
doaj  

Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]

, 2018
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast, AD Michelson, B Labarthe, B Shen, C Patrono, CT Ammollo, D Capodanno, D Gailani, DA Gorog, Diana A. Gorog, DM Coenen, E Álvarez, ER Bates, F Kabirian, F Müller, F Semeraro, G Stephens, H Brogren, HE Speich, HE Speich, HJ Weiss, HJ Weiss, HR Baumgartner, J Zilberman-Rudenko, JD McFadyen, JI Weitz, JM Cosemans, JP Collet, JP Collet, K Hosokawa, K Nagatsuka, KS Sakariassen, L Valerio, LF Brass, M Cattaneo, M Farag, M Humbert, M Larsson, M Li, M Ungerer, MA Bailey, MI Furman, MJ Price, ML Montfoort von, MS Sabatine, P Andre, P Seizer, PA Borne von dem, PP Wadowski, R Hellmuth, R Nergiz-Unal, RA Ajjan, S Goto, S Goto, SA Shaya, SB Larsen, SJ Marciniak, T Heitzer, T Renné, VT Turitto, VT Turitto, WA Schumacher, WS Nesbitt, X Wang, Y Yano, YC Lau, ZM Ruggeri   +66 more
core   +2 more sources

Recent Advances in Collective Behaviors of Micro/Nanomotor Swarms

Advanced Materials, EarlyView.
This review describes the driving forces behind collective motion, explores the self‐organization of micro/nano swarms across zero‐dimensional (0D), one‐dimensional (1D), two‐dimensional (2D), and three‐dimensional (3D) spaces, and highlights their potential in drug delivery, environmental monitoring, and smart devices.
Siwen Sun, Bingbing Sun, Alexander B. Cook, Tania Patiño Padial, Jan C. M. van Hest   +4 more
wiley   +1 more source

Endothelial protease-activated receptor 4: impotent or important?

Frontiers in Cardiovascular Medicine
The protease thrombin, which increases its levels with various pathologies, can signal through the G protein-coupled receptors protease-activated receptors 1 and 4 (PAR1/PAR4). PAR1 is a high-affinity receptor for thrombin, whereas PAR4 is a low-affinity
Rahul Rajala, Rahul Rajala, Rahul Rajala, Courtney T. Griffin, Courtney T. Griffin   +4 more
doaj   +1 more source

Multiplexed Luminal Tissue Constructs with Reconfigurable Barriers for Dynamic Modeling of Multi‐Tissue Interactions

Advanced Materials Technologies, EarlyView.
This study describes the fabrication of arrays of luminal tissue constructs for 3D luminal tissue modeling. An oil or media‐filled reservoir between constructs serves as a liquid barrier or bridge to regulate communication between lumens within the array for modeling multi‐tissue interactions in vitro. Abstract Cell‐lined luminal structures are crucial
Mouhita Humayun, José A. Jiménez‐Torres, Chao Li, Jose M. Ayuso, Karina Lugo‐Cintron, Joseph Ulbrich, Benjamin Myers, Sheena C. Kerr, Adeel Ahmed, David J. Beebe   +9 more
wiley   +1 more source

Global Thrombosis Test - a possible monitoring system for the effects and safety of dabigatran [PDF]

, 2015
© Otsui et al. 2015BACKGROUND: Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a
Gorog, Diana A, Inoue, Nobutaka, Iwata, Sachiyo, Otsui, Kazunori, Ozawa, Toru, Suzuki, Atsushi, Takei, Asumi, Yamamoto, Junichiro, Yoshioka, Takayuki   +8 more
core   +2 more sources

Directed Navigation of Magnetotactic Bacteria via Magnetotaxis in a 3D Vasculature‐On‐A‐Chip

Advanced Materials Technologies, EarlyView.
A perfusable vascular network is developed to investigate MTB at the single‐microorganism level. MTB is demonstrated to successfully align and navigate along the magnetic field inside the microvessels. Abstract Magnetotactic bacteria (MTB), inherently motile and self‐powered, are promising biorobotic candidates for targeted anti‐cancer drug delivery ...
Brianna Bradley, Yuji Nashimoto, Aldo Gonzalez‐Lopez, Takeshi Hori, Hirokazu Kaji, Peter L. Davies, Carlos Escobedo   +6 more
wiley   +1 more source