Results 111 to 120 of about 288,586 (288)

Platelets and thrombin generation.

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2002
This review examines the evidence that platelets play a major role in localizing and controlling the burst of thrombin generation leading to fibrin clot formation.
D. Monroe, M. Hoffman, H. Roberts
semanticscholar   +1 more source

Use of microfluidics to assess the platelet-based control of coagulation

open access: yesPlatelets, 2017
This paper provides an overview of the various types of microfluidic devices that are employed to study the complex processes of platelet activation and blood coagulation in whole blood under flow conditions. We elaborate on how these devices are used to
Magdolna Nagy   +2 more
doaj   +1 more source

Regulation of Acetylcholine Quantal Release by Coupled Thrombin/BDNF Signaling in Mouse Motor Synapses

open access: yesCells, 2019
The aim of this study was to compare the acute effects of thrombin and brain-derived neurotrophic factor (BDNF) on spontaneous miniature endplate potentials (MEPPs) and multiquantal evoked endplate potentials (EPPs) in mouse neuromuscular junctions (NMJs)
Alexander Gaydukov   +6 more
doaj   +1 more source

Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors [PDF]

open access: yes
Aptamer functionalized addressable SWNT-film arrays between cantilever electrodes were successfully developed for biosensor applications. Dielectrophoretically aligned SWNT suspended films made possible highly specific and rapid detection of target ...
An, T, HAHN, SEI KWANG, Kim, KS, Lim, G
core   +1 more source

The transfer of VLDL-associated phospholipids to activated platelets depends upon cytosolic phospholipase A2 activity

open access: yesJournal of Lipid Research, 2007
We previously reported that VLDL could transfer phospholipids (PLs) to activated platelets. To identify the metabolic pathway involved in this process, the transfer of radiolabeled PLs from VLDL (200 μM PL) to platelets (2 × 108/ml) was measured after ...
Salam Ibrahim   +4 more
doaj  

Mechanical strain induces growth of vascular smooth muscle cells via autocrine action of PDGF. [PDF]

open access: yes, 1993
The effect of cyclic mechanical strain on growth of neonatal rat vascular smooth muscle (VSM) cells were examined. Cells were grown on silicone elastomer plates subjected to cyclic strain (60 cycle/min) by application of a vacuum under the plates. A 48 h
Ives, HE   +4 more
core  

GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets. [PDF]

open access: yes, 2020
G protein-coupled receptors (GPCRs) mediate the majority of platelet activation in response to agonists. However, questions remain regarding the mechanisms that provide negative feedback toward activated GPCRs to limit platelet activation and thrombus ...
Benovic, Jeffrey   +13 more
core   +1 more source

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