Results 21 to 30 of about 288,586 (288)
Haematologica, 2008 Background Thrombin generation has been shown to reflect coagulation potential and factor VIII (FVIII) levels in patients with hemophilia A. We hypothesize that thrombin generation in the presence of thrombomodulin reflects plasma FVIII levels better ...
Arne W.J.H. Dielis +6 more
doaj +1 more source
Journal of Clinical Interventional Radiology ISVIR, 2021 Purpose To describe our initial experience with percutaneous thrombin injection combined with endovascular coiling of high-flow visceral artery pseudoaneurysms. Materials and Methods Institutional review board approval was obtained.
Kalpana Sivalingam +2 more
doaj +1 more source
Mechanisms of modulation of brain microvascular endothelial cells function by thrombin. [PDF]
, 2017 Brain microvascular endothelial cells are a critical component of the blood-brain barrier. They form a tight monolayer which is essential for maintaining the brain homeostasis.
Abood, Mary E. +4 more
core +2 more sources
Thrombin Generation and Cancer: Contributors and Consequences
Cancers, 2019 The high occurrence of cancer-associated thrombosis is associated with elevated thrombin generation. Tumour cells increase the potential for thrombin generation both directly, through the expression and release of procoagulant factors, and indirectly ...
C. Reddel, C. Tan, V. Chen
semanticscholar +1 more source
Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. [PDF]
, 2000 Protease-activated receptor (PAR)-1 is a cellular receptor for thrombin that is activated after proteolytic cleavage. The contribution of PAR-1 to inflammatory cell-mediated renal injury was assessed in murine crescentic glomerulonephritis (GN).
Bernatowicz +33 more
core +3 more sources
Calibrated Automated Thrombin Generation Measurement in Clotting Plasma
Pathophysiology of Haemostasis and Thrombosis, 2003 Calibrated automated thrombography displays the concentration of thrombin in clotting plasma with or without platelets (platelet-rich plasma/platelet-poor plasma, PRP/PPP) in up to 48 samples by monitoring the splitting of a fluorogenic substrate and ...
H. Hemker +7 more
semanticscholar +1 more source
Scientific Reports, 2017 Cells release diverse types of vesicles constitutively or in response to proliferation, injury, inflammation, or stress. Extracellular vesicles (EVs) are crucial in intercellular communication, and there is emerging evidence for their roles in ...
C. Tripisciano +6 more
semanticscholar +1 more source
Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts [PDF]
, 2005 Rho is a major small GTP-binding protein that is involved in the regulation of various cell functions, including proliferation and cell migration, through activation of multiple signaling molecules in various types of cells.
Kurose, Hitoshi +4 more
core +2 more sources
Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia. [PDF]
, 2015 BackgroundTwo congenital bleeding diatheses have been identified in Thoroughbred horses: Glanzmann thrombasthenia (GT) and a second, novel diathesis associated with abnormal platelet function in response to collagen and thrombin stimulation.Hypothesis ...
Blevins, G +4 more
core +1 more source
Thrombin‐Responsive Transcutaneous Patch for Auto‐Anticoagulant Regulation
Advances in Materials, 2017 A thrombin-responsive closed-loop patch is developed for prolonged heparin delivery in a feedback-controlled manner. This microneedle-based patch can sense activated thrombin and subsequently releases heparin to prevent coagulation in the blood flow ...
Yuqi Zhang +11 more
semanticscholar +1 more source