Results 41 to 50 of about 158,309 (195)

Thrombin-Induced Responses via Protease-Activated Receptor 1 Blocked by the Endothelium on Isolated Porcine Retinal Arterioles

open access: yes, 2018
Purpose: Thrombin, a serine protease, causes organ-specific responses to vessels. However, the mechanism by which thrombin affects the retinal microcirculation remains unclear.
Akira Tanner (5549972)   +5 more
core   +1 more source

Bare magnetic nanoparticles as fluorescence quenchers for detection of thrombin [PDF]

open access: yes, 2015
Rapid and sensitive detection of thrombin has very important significance in clinical diagnosis. In this work, bare magnetic iron oxide nanoparticles (magnetic nanoparticles) without any modification were used as fluorescence quenchers. In the absence of
Dong, Tingting   +4 more
core   +1 more source

Thrombin activatable fibrinolysis inhibitor como preditor de sangramento no transplante hepático: estudo piloto observacional

open access: yesRevista Brasileira de Terapia Intensiva
RESUMO Objetivo: Correlacionar os níveis de thrombin activatable fibrinolysis inhibitor no pós-operatório imediato e com 24 horas de pós-operatório com o volume de sangramento tansoperatório.
Wagner Luis Nedel   +2 more
doaj   +1 more source

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

open access: yes, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Ferdinand Bohmann   +20 more
core   +2 more sources

Circulating Extracellular Vesicles Are Strongly Associated With Cardiovascular Risk Markers

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundExtracellular vesicles (EVs) are submicron membrane-bound vesicles released from various cells, which are emerging as a potential novel biomarker in cardiovascular diseases (CVDs) due to their procoagulatory and prothrombotic properties ...
Ruihan Zhou   +3 more
doaj   +1 more source

Core and shell platelets of a thrombus: A new microfluidic assay to study mechanics and biochemistry

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Background Hemostatic clots have a P‐selectin positive platelet core covered with a shell of P‐selectin negative platelets. Objective To develop a new human blood microfluidic assay to interrogate core/shell mechanics.
Michael E. DeCortin   +2 more
doaj   +1 more source

Modulation of the Thrombin Pathway Restores LTP in a Pilocarpine Mice Model of Status Epilepticus

open access: yesFrontiers in Cellular Neuroscience, 2022
BackgroundStatus epilepticus (SE) leads to memory impairment following a seizure, attributed to long-term potentiation (LTP) reduction. Thrombin, a coagulation factor that activates protease-activated receptor 1 (PAR1) is involved in cognitive impairment
Efrat Shavit-Stein   +14 more
doaj   +1 more source

Interplay Between Angiotensin II Type 1 Receptor and Thrombin Receptor Revealed by Bioluminescence Resonance Energy Transfer Assay

open access: yesFrontiers in Pharmacology, 2020
The key hormone of the renin-angiotensin system (RAS), angiotensin II (AngII), and thrombin are known to play major roles in the vascular system and its related disorders.
Isra Al Zamel   +4 more
doaj   +1 more source

Inhibition of Angiopoietin-2 Production by Myofibrocytes Inhibits Neointimal Hyperplasia After Endoluminal Injury in Mice

open access: yesFrontiers in Immunology, 2018
Fibrocytes are myeloid lineage cells implicated in wound healing, repair, and fibrosis. We previously showed that fibrocytes are mobilized into the circulation after vascular injury, including the immune-mediated injury that occurs after allogeneic ...
Daxin Chen   +9 more
doaj   +1 more source

Microheology of fibrin clots [PDF]

open access: yes, 2012
An active particle tracking microrheology technique has been developed to study the viscoelastic properties of human fibrin and plasma clots. In order to perform microrheology measurements, a magnetic microrheometer device has been adapted and a ...
Allan, Peter
core   +4 more sources

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