Results 51 to 60 of about 158,309 (195)
Nicotine’s impact on platelet function: insights into hemostasis mechanisms
Frontiers in PharmacologyIntroductionTraditional Miao and Dai Chinese medicines have used nicotine-rich leaf tobacco to treat traumatic injuries by promoting hemostasis. While nicotine is known to enhance platelet aggregation, its effects on other platelet functions and ...
Xiayu Wu +18 more
doaj +1 more source
, 2008 Osteosarcoma is a very malignant bone tumor which has a high metastatic potential and usually lead to poor prognosis. The adhesion of tumor cells to the endothelium or extracellular matrix (ECM) is an essential step in the metastatic cascade.
YANG, RONG-SEN;TANG, CHIH-HSIN;YEH, CHIA-HSIN;HUANG, TUR-FU +1 more
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Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures
Molecules, 2016 The regulation of thrombin activity offers an opportunity to regulate blood clotting because of the central role played by this molecule in the coagulation cascade. Thrombin-binding DNA aptamers have been used to inhibit thrombin activity.
Abhijit Rangnekar +4 more
doaj +1 more source
, 1995 The interaction of rabbit lung thrombomodulin (TM) and C-terminal hirudin 54-65 fragment (Hir54-65) with human alpha-thrombin were investigated by exploiting their competitive inhibition of thrombin-fibrinogen interaction.
De Cristofaro, Raimondo +3 more
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, 2009 Thrombin is a key factor in the stimulation of fibrin deposition, angiogenesis and proinflammatory processes. Abnormalities in these processes are primary features of rheumatoid arthritis (RA) in synovial tissues.
邱詠証;馮逸卿;賴志河;洪千惠;許弘昌;李土生;楊榮森;符文美;湯智昕 +1 more
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Percutaneous Thrombin Injection for the Treatment of Post-Procedural Iatrogenic Pseudoaneurysms
대한영상의학회지, 2019 Purpose To report our clinical experience of thrombin injection for iatrogenic pseudoaneurysms of peripheral arteries with or without balloon dilatation and coil embolization as adjunctive techniques.
Sohee Park +5 more
doaj +1 more source
Research and Practice in Thrombosis and Haemostasis, 2020 Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten +3 more
doaj +1 more source
Annales pharmaceutiques francaises, 1986 Thrombosis, either venous and arterial, is the most important cause of death in our society. Thrombin formation is a pivotal step in the pathogenesis of both forms of thrombosis. Drugs like heparin and vitamin K antagonists act because they inhibit thrombin formation.
Hemker, H.C., Beguin, S.
openaire +2 more sources
Frontiers in Immunology, 2018 BackgroundThe interaction of coagulation factors has been shown to go beyond their traditional roles in hemostasis and to affect the development of inflammatory diseases.
Kerstin Göbel +5 more
doaj +1 more source
Inherited anti-thrombin deficiency in a Malay-Malaysian family: a missense mutation at nucleotide g.13267C>A aka anti-thrombin Budapest 5 (p.Pro439Thr) of the SERPINC 1 gene [PDF]
, 2014 OBJECTIVE: Inherited anti-thrombin deficiency is an autosomal dominant disorder which is associated with increased risk for venous thromboembolism (VTE). This condition is very rare in Malaysia and there has been no documented report. Thus, the aim of
O., Nur Nadia +5 more
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