Results 71 to 80 of about 162,133 (299)

Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures

open access: yesMolecules, 2016
The regulation of thrombin activity offers an opportunity to regulate blood clotting because of the central role played by this molecule in the coagulation cascade. Thrombin-binding DNA aptamers have been used to inhibit thrombin activity.
Abhijit Rangnekar   +4 more
doaj   +1 more source

Thrombin-Induced Il-6 Production in Human Synovial Fibroblasts Is Mediated by Par1, Phospholipase C, Protein Kinase C Alpha, C-Src, Nf- Kappab and P300 Pathway

open access: yes, 2009
Thrombin is a key factor in the stimulation of fibrin deposition, angiogenesis and proinflammatory processes. Abnormalities in these processes are primary features of rheumatoid arthritis (RA) in synovial tissues.
邱詠証;馮逸卿;賴志河;洪千惠;許弘昌;李土生;楊榮森;符文美;湯智昕   +1 more
core  

Thrombin receptor-activating peptide sensitizes the human endothelial thrombin receptor

open access: yes, 1995
Receptor-operated effects of alpha-thrombin and of the thrombin receptor-activating peptide TRAP14 on cytoplasmic Ca2+ concentration ([Ca2+]i) were examined in fura 2-loaded endothelial cells.
C. Mayerhofer   +3 more
core   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

open access: yesAdvanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer   +12 more
wiley   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

open access: yesAdvanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong   +5 more
wiley   +1 more source

Percutaneous Thrombin Injection for the Treatment of Post-Procedural Iatrogenic Pseudoaneurysms

open access: yes대한영상의학회지, 2019
Purpose To report our clinical experience of thrombin injection for iatrogenic pseudoaneurysms of peripheral arteries with or without balloon dilatation and coil embolization as adjunctive techniques.
Sohee Park   +5 more
doaj   +1 more source

Thrombin generation in a woman with heterozygous factor V Leiden and combined oral contraceptives: A case report

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten   +3 more
doaj   +1 more source

Rhodostomin Inhibits Thrombin-Enhanced Adhesion of Ros 17/2.8 Cells through the Blockade of αvβ3 Integrin

open access: yes, 2008
Osteosarcoma is a very malignant bone tumor which has a high metastatic potential and usually lead to poor prognosis. The adhesion of tumor cells to the endothelium or extracellular matrix (ECM) is an essential step in the metastatic cascade.
YANG, RONG-SEN;TANG, CHIH-HSIN;YEH, CHIA-HSIN;HUANG, TUR-FU   +1 more
core  

Cross-Reactivity of Rabbit Anti-Bovine Thrombin IgGs With Human α-Thrombin and a Recombinant Version of Human Thrombin (Recothrom)

open access: yes, 2010
It has been reported that patients exposed to topical bovine thrombin preparations may develop antibodies against bovine thrombin, factr V or various other proteins found in these preparations.
Josephine Cunanan   +3 more
core   +1 more source

Re‐Thinking Electronic Circuit Design Through Emerging Reconfigurable Field Effect Transistors

open access: yesAdvanced Science, EarlyView.
Graphical illustration of reconfigurable field effect transistor (RFET) operation modes, including n‐type, p‐type, and ambipolar transport, as well as their areas of application discussed in this review: digital circuit design, analog circuit design, post‐Shannon computing, and sensing. ABSTRACT Reconfigurable field‐effect transistors, short RFETs, are
Jens Trommer   +19 more
wiley   +1 more source

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