Results 71 to 80 of about 203,879 (305)

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

Percutaneous Thrombin Injection for the Treatment of Post-Procedural Iatrogenic Pseudoaneurysms

open access: yes대한영상의학회지, 2019
Purpose To report our clinical experience of thrombin injection for iatrogenic pseudoaneurysms of peripheral arteries with or without balloon dilatation and coil embolization as adjunctive techniques.
Sohee Park   +5 more
doaj   +1 more source

Thrombin generation in a woman with heterozygous factor V Leiden and combined oral contraceptives: A case report

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten   +3 more
doaj   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

open access: yesAdvanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr   +19 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu   +26 more
wiley   +1 more source

The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders—A Systematic Review

open access: yesFrontiers in Immunology, 2018
BackgroundThe interaction of coagulation factors has been shown to go beyond their traditional roles in hemostasis and to affect the development of inflammatory diseases.
Kerstin Göbel   +5 more
doaj   +1 more source

Engineered Au@CeO2 Hybrid Nanoparticles With Microenvironment Dependent Self‐Adjustability for Integration of Tumor‐Specific Photothermal‐Chemodynamic Therapy and Inflammation Prevention

open access: yesAdvanced Science, EarlyView.
An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu   +8 more
wiley   +1 more source

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

open access: yesAngewandte Chemie, EarlyView.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang   +12 more
wiley   +2 more sources

Oxidative stress model of lipopolysaccharide combined with thrombin inducing in broiler chicks

open access: yesFrontiers in Veterinary Science
Lipopolysaccharides (LPS) are commonly used to construct inflammation models. However, poultry have a certain degree of tolerance to LPS due to the lack of thrombin XI and XII in their bodies. Thrombin activation produces clotting factors that can cleave
Huiyu Shi   +10 more
doaj   +1 more source

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