Results 21 to 30 of about 162,133 (299)
Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function. [PDF]
PLoS ONE, 2016 Thrombin is a highly plastic molecule whose activity and specificity are regulated by exosites 1 and 2, positively-charged domains that flank the active site. Exosite binding by substrates and cofactors regulates thrombin activity by localizing thrombin,
Calvin H Yeh +4 more
doaj +1 more source
Cardiovascular Diabetology, 2018 Background As a strong platelet agonist on the one hand and key molecule in plasmatic coagulation on the other hand, thrombin connects primary and secondary hemostasis.
Silvia Lee +4 more
doaj +1 more source
Thrombin-antithrombin complexes in envenomated dogs and controls.
, 2022 Concentrations of thrombin-antithrombin (TAT) complexes in envenomated dogs at five timepoints after bite (black dots) and controls (green dots). T1 = presentation, T2 = 12 hours, T3 = 24 hours, T4 = 36 hours and T5 = 15 days after bite.* indicates P < 0.
Hannah J. Harjen (10587731) +8 more
core +1 more source
Thrombin-induced changes in syndecan ectodomain proteins from ex vivo human lung.
, 2019 ELISA was performed to measure the concentration of each of the syndecan ectodomains in the supernatant of fresh human lung slices treated with vehicle or thrombin.
Jamie E. Meegan (6703580) +4 more
core +1 more source
Safety of topical thrombins: the ongoing debate
Patient Safety in Surgery, 2009 Until recently, only bovine-derived thrombin was available for use as a stand-alone topical hemostat or as a component of other hemostatic devices. Concerns over a number of case reports of immune-mediated coagulopathies associated with the use of bovine-
Lomax Christopher
doaj +1 more source
Antibodies, 2020 Platelet factor 4 (PF4, CXCL4) is a small chemokine protein released by activated platelets. Although a major physiological function of PF4 is to promote blood coagulation, this cytokine is involved in innate and adaptive immunity in events when ...
Zheng Cai +3 more
doaj +1 more source
Bare magnetic nanoparticles as fluorescence quenchers for detection of thrombin [PDF]
, 2015 Rapid and sensitive detection of thrombin has very important significance in clinical diagnosis. In this work, bare magnetic iron oxide nanoparticles (magnetic nanoparticles) without any modification were used as fluorescence quenchers. In the absence of
Dong, Tingting +4 more
core +1 more source
PURIFICATION OF THROMBIN [PDF]
Journal of General Physiology, 1942 1. Under certain conditions crude prothrombin changes to thrombin without the addition of extraneous activators and in the absence of ionic calcium. 2. Thrombin is soluble in 0.45 saturated ammonium sulfate, whereas crude prothrombin is not. 3.
openaire +2 more sources
, 2018 Purpose: Thrombin, a serine protease, causes organ-specific responses to vessels. However, the mechanism by which thrombin affects the retinal microcirculation remains unclear.
Akira Tanner (5549972) +5 more
core +1 more source