Results 151 to 160 of about 3,246,752 (251)

Understanding exosomes: A history of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), including exosomes, have emerged as fundamental regulators of cell‐to‐cell communication and are increasingly recognized for their therapeutic and diagnostic promise. While EV research has expanded remarkably over the past two decades, the discipline is rooted in a much longer history of observations ...
Richard J. Miron, Paras Ahmad, Anton Sculean   +2 more
wiley   +1 more source

Computational Modeling of Pro-inflammatory Cytokine-Enhanced Blood Coagulation. [PDF]

Comput Struct Biotechnol J
Li G, Zhao C, Frydman GH, Li H.
europepmc   +1 more source

New Insights Into Pathogenesis, Diagnostics, and Therapeutic Options for Canine Angiostrongylosis

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To provide a comprehensive overview of Angiostrongylus vasorum infection in dogs, with a particular emphasis on recent developments in the understanding of disease pathophysiology and an update on developments in diagnostic and therapeutic options.
Iris Elgueta, Daniel Lewis, Eric R. Morgan, Jenny Helm   +3 more
wiley   +1 more source

P125 | CLINICAL OF USE OF THROMBIN GENERATION AND D-DIMER TO PERSONALIZE LONG TERM ANTITHROMBOTIC TREATMENT IN CANCER PATIENTS.

Haematologica
Venous thromboembolism (VTE) is a frequent complication in cancer patients. While there is conclusive evidence on treatment during the acute phase, data on secondary prophylaxis remain limited.
A. Frolli, M. Fonte, B. Montaruli, G. Valabrega, M. Bullo, J. Umurungi   +5 more
doaj  

Senescent cardiac cells promote thrombus formation and impair fibrinolysis. [PDF]

Geroscience
Shahar T, Ezra N, Chen S, Kryukov O, Cohen S.   +4 more
europepmc   +1 more source

COMPUTATIONAL STUDY FOR BINDING OF OSCILLARIN TO HUMAN alpha-THROMBIN

, 2009
Quantum mechanical calculation and molecular dynamics simulation have been carried out to study binding of Oscillarin (OSC), an antithrombotic marine natural product to human alpha-thrombin.
韩克利, Wu, Emilia L., Han, Keli, Zhang, John Z. H.   +3 more
core  

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Thrombin generation, viscoelastic coagulation profiles, and disease severity in critically Ill COVID-19 patients: a prospective observational study. [PDF]

BMC Anesthesiol
Espeter F, Garczarek L, Künne D, Kuhlmann H, Heitmeier S, Schmoch T, Brenner T, Schmidt K.   +7 more
europepmc   +1 more source

HDXMS Reveals Dynamic Changes in the Anticoagulant W215A Mutant of Thrombin [PDF]

Biophysical Journal, 2017
Riley Peacock, Jessie Davis, Sofia Zaragosa, Elizabeth Komives   +3 more
openaire   +1 more source

Peripheral regeneration of Aβ low‐threshold mechanoreceptors is limited despite activation of regenerative transcriptional pathways

The Journal of Physiology, EarlyView.
Abstract figure legend The regeneration of Aβ low‐threshold mechanoreceptors (Aβ‐LTMRs), sensory neurons responsible for discriminative touch, has not previously been explored. Here, we took advantage of the selective expression of Calb1 in Aβ‐LTMRs to generate two genetic mouse models for studying their regenerative response after nerve injury.
Sara Bolívar, Natàlia Martínez‐Mateu, David Ovelleiro, Esther Udina   +3 more
wiley   +1 more source