Venous thromboembolism (VTE) is a frequent complication in cancer patients. While there is conclusive evidence on treatment during the acute phase, data on secondary prophylaxis remain limited.
A. Frolli +5 more
doaj
TMEM16A channel signalling microdomains in the regulation of vascular function
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
In silico analysis of patient specific coagulation and flow effects on fibrin clot formation. [PDF]
Cruts JMH +6 more
europepmc +1 more source
HDXMS Reveals Dynamic Changes in the Anticoagulant W215A Mutant of Thrombin [PDF]
Riley Peacock +3 more
openaire +1 more source
Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda +5 more
wiley +1 more source
A personal 360° view of applications of ‘biomimetic’ molecular recognition
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley +1 more source
Gut metabolite TMAO and its structural analogs bind to fibrinogen thereby enhancing clot formation: a rationale for atherosclerosis risk. [PDF]
Singh K +5 more
europepmc +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
In a large multicenter cohort, a low serum calcium‐to‐potassium (Ca/K) ratio (< 0.55) in the third trimester was a novel risk factor for postpartum venous thromboembolism (VTE). This association was partly explained by concomitant variations in hemoglobin and D‐dimer levels, pointing to integrated management of electrolytes and anemia for postpartum ...
Qian Li +10 more
wiley +1 more source
Understanding pressure excursions in extracorporeal technologies: The role of shear stress and hematologic predisposition. [PDF]
El Dsouki Y +3 more
europepmc +1 more source

