Results 161 to 170 of about 3,246,752 (251)

Assessment of Hypercoagulability After Orthopedic Trauma Surgery Using Coagulation Biomarkers and TEG/ROTEM. [PDF]

Int J Mol Sci
Huzum B, Cionca DV, Ciupilan D, Tesoi DF, Mircea C, Badulescu OV.   +5 more
europepmc   +1 more source

Global analysis of thermal and chemical denaturation using CheMelt: Thermodynamic dissection of highly thermostable de novo designed proteins

Protein Science, Volume 35, Issue 11, November 2026.
Abstract De novo protein design often produces thermostable proteins that denature above 100°C, which complicates the analysis of their stability. Thermostable proteins can be unfolded by combined chemical and thermal denaturation followed by global analysis of multiple melting curves.
Vili Lampinen, Osvaldo Burastero, Iara Plácido Guazzelli, Florian Vögele, Francisca Pinheiro, Jan S. Nowak, Maria M. Garcia Alai, Magnus Kjaergaard   +7 more
wiley   +1 more source

General Dynamics News

, 1966
Biweekly newsletter published for employees of the General Dynamics Fort Worth Division containing work-related information, updates about employees, and other ...
General Dynamics Corporation. Convair Division.
core  

Quantitative and amino acid sequence analysis of soluble HIV‐1 Vpu and calmodulin interactions

Protein Science, Volume 35, Issue 11, November 2026.
Abstract HIV‐1 Vpu supports viral adaptation through host‐protein interactions. Although mainly membrane‐associated, we recently identified a soluble Vpu form that forms a stable complex with Ca2+‐bound calmodulin (Ca2+–CaM), potentially influencing Vpu trafficking. Here, to determine the binding affinity and identify regions of soluble Vpu involved in
Adeyemi Ogunbowale, Elaheh Hadadianpour, Olamide Ishola, Md Majharul Islam, Natalie Ramos, Arvin Saffarian Delkhosh, Elka R. Georgieva   +6 more
wiley   +1 more source

General Dynamics News

, 1968
Biweekly newsletter published for employees of the General Dynamics Fort Worth Division containing work-related information, updates about employees, and other ...
General Dynamics Corporation. Convair Division.
core  

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Linking hemostasis to bone health in bleeding disorders. [PDF]

Blood Adv
Machin N.
europepmc   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2605-2612, October 2026.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

Complementary targeted constructs factor XI/XIa inhibition. [PDF]

Blood Adv
Becker RC.
europepmc   +1 more source

Mast Cell–Microglia Crosstalk Drives Aberrant Synaptic Pruning Through PAR‐2/MAPK/NF‐κB Signaling in Neonatal Hypoxic–Ischemic Encephalopathy

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Following neonatal hypoxic–ischemic injury, hippocampal mast cell degranulation releases tryptase, which activates microglial PAR‐2 receptors to trigger p38 MAPK/NF‐κB signaling and drive aberrant synaptic engulfment. This pathological mast cell–microglia crosstalk leads to progressive synaptic loss and long‐term cognitive impairment.
Yanping Yang, Dingliang Cai, Jingwen Yu, Yixiao Zhu, Yongxin Huang, Yubing Lin, Chengqian Teng, Jianjie Wei, Ying Lin, Dongsheng Dai, Fushan Xue, Andi Chen, Xiaochun Zheng, Xiaohui Chen   +13 more
wiley   +1 more source