Results 181 to 190 of about 3,246,752 (251)
Cyclomulberrin from <i>Morus alba</i> L. exerts antithrombotic effects by modulating platelet activation: an integrated network pharmacology and <i>in vitro</i> study. [PDF]
Guo Y, He R, Peng J, Yuan S, Ma Y, Li Q.
europepmc +1 more source
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang +12 more
wiley +2 more sources
Threading Precision: Progress and Emerging Trends in Aptamer-Based Nanopore Sensing. [PDF]
Sett A.
europepmc +1 more source
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa +5 more
wiley +1 more source
ABSTRACT Borderline prolongation of routine clotting assays—particularly the activated partial thromboplastin time (aPTT)—is a common interpretative challenge in laboratory hematology. These reproducible but mildly prolonged results often lie just beyond the upper reference limit and can trigger unnecessary follow‐up, delays, or misinterpretation ...
Nikolaos Androulakis +3 more
wiley +1 more source
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee +5 more
wiley +2 more sources
Correction: Haemostatic changes during CART cell therapy and risk of complications. [PDF]
Panizo-Inogés M +12 more
europepmc +1 more source
An Automated Microfluidic System for Haemostasis Assessment in Cirrhosis With Thrombocytopenia
ABSTRACT Background & Aims Conventional laboratory tests do not capture platelet–vessel wall interactions (primary haemostasis) occurring in vivo, limiting guidance before invasive procedures. This is relevant in patients with thrombocytopenia, hallmark of advanced cirrhosis. Microfluidic assays may overcome these limitations.
Niccolò Bitto +14 more
wiley +1 more source
Thrombin generation parameters provide independent information on plasma coagulation potential in pediatric patients on extracorporeal membrane oxygenation: a prospective, single-center pilot study. [PDF]
Mehic D +7 more
europepmc +1 more source

