Results 191 to 200 of about 3,246,752 (251)

Obesity‐Related Coagulation Activation in Adolescents and Children: A Systematic Review and Meta‐Analysis

Obesity Reviews, Volume 27, Issue 10, October 2026.
Obesity is widely recognized as a pro‐thrombotic condition, yet the specific biomarker profile reflecting coagulation activation remains incompletely defined. Obesity is associated with increased coagulation activation, particularly in children, suggesting an early pro‐thrombotic shift.
Julia Buchold, Hans‐Jonas Meyer, Manuel Florian Struck, Shrey Kohli, Akash Mathew, Gyulten Mangova, Alexey Surov, Matthias Blüher, Berend Isermann, Silke Zimmermann   +9 more
wiley   +1 more source

Thrombin generation profiling in multiple myeloma: a comprehensive evaluation of prothrombotic state. [PDF]

Blood Coagul Fibrinolysis
Miele C, Vasco A, Manfredi L, Randa I, Della Pepa R, Puzone S, Addesso R, Di Vico V, Tinto N, Frisso G, Scudiero O, Marcella S, Mazzaccara C.   +12 more
europepmc   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils. [PDF]

Adv Sci (Weinh)
Mohr J, Schmitz A, Dinarvand M, Wulfert F, Shankar S, Hill BF, Wojak M, Gretz J, Britz M, Neubert E, Shumanska M, Kaushik S, Kartaschew L, Bogeski I, Daniel J, Jung S, Eble J, Wabnitz G, Erpenbeck L, Kruss S.   +19 more
europepmc   +1 more source

Discovery of a Reversible Sub‐Picomolar Thrombin Inhibitor Using DCC

Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.
An ultrapotent yet fully reversible trivalent thrombin inhibitor discovered through screening a large dynamic combinatorial library (DCL) of 125 000 members of self‐assembled fragments. The innovative approach leverages size‐exclusion‐based affinity selection, coupled with MALDI‐TOF mass spectrometry readout, enabling the full workflow to be completed ...
Millicent Dockerill, Richard J. Payne, Nicolas Winssinger   +2 more
wiley   +2 more sources

Ultra-Low Dose Argatroban in Heparin-Induced Thrombocytopenia with Thrombocytopenia and Hypofibrinogenemia: A Case Report. [PDF]

TH Open
Shi C, Cai T, Yue M, Ma H, Qin Q, Song Q.   +5 more
europepmc   +1 more source

Gut metabolite TMAO and its structural analogs bind to fibrinogen thereby enhancing clot formation: a rationale for atherosclerosis risk. [PDF]

Sci Rep
Singh K, Kumari A, Bakhshi R, Varmani SG, Gupta A, Singh LR.   +5 more
europepmc   +1 more source

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

Chemistry – A European Journal, Volume 32, Issue 36, 24 September 2026.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma, Peter A. C. Wing, Wojtek Treyde, Shyam Basak, Simeon D. Draganov, Taylah Andrews‐Clark, Eidarus Salah, Petra Lukacik, Claire Strain‐Damerell, Adán Pinto‐Fernández, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield, Lennart Brewitz   +13 more
wiley   +1 more source

Whole-blood coagulation and platelet dynamics identify differential prothrombotic states in patients with rheumatoid arthritis treated with JAK or TNF-ɑ inhibitors. [PDF]

RMD Open
Giollo A, Di Luozzo L, Salvato M, Khalid K, D'Andrea R, Benetti A, Samà C, Ramonda R, Simioni P, Spiezia L.   +9 more
europepmc   +1 more source

Understanding pressure excursions in extracorporeal technologies: The role of shear stress and hematologic predisposition. [PDF]

J Extra Corpor Technol
El Dsouki Y, Cirullo C, D'Alessandro A, Condello I.   +3 more
europepmc   +1 more source

A refined phenomenological model of viscoelastic clot formation and lysis in trauma-induced coagulopathy. [PDF]

Front Cardiovasc Med
Liu G, Shick AE, Shamash M, Cook CM, Molina ML, Cohen MJ, Menezes AA.   +6 more
europepmc   +1 more source