Results 221 to 230 of about 100,897 (348)

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

Altered thrombin generation with prothrombin complex concentrate is not detected by viscoelastic testing: an in vitro study. [PDF]

Br J Anaesth
Hofmann N, Schöchl H, Zipperle J, Gratz J, Schmitt FCF, Oberladstätter D.   +5 more
europepmc   +1 more source

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

, 2008
Erik I. Tucker, Ulla M. Marzec, Tara C. White, Sawan Hurst, Sandra Rugonyi, Owen J. T. McCarty, David Gailani, András Gruber, Stephen R. Hanson   +8 more
openalex   +1 more source

Thrombin Generation is Associated with Venous Thrombo-embolism Recurrence, but not with Major Bleeding and Death in the Elderly: A Prospective Multicenter Cohort Study

, 2023
Kristina Vrotniakaite-Bajerciene, Sereina Rütsche, Sara Calzavarini, Claudia Quarroz, Odile Stalder, Marie Méan, Marc Righini, Daniel Staub, Jürg H. Beer, Beat Frauchiger, Joseph Österwalder, Nils Kucher, Christian M. Matter, Marc Husmann, Martin Banyai, Markus Aschwanden, Lucia Mazzolai, Olivier Hügli, Nicolas Rodondi, Drahomir Aujesky, Anne Angelillo‐Scherrer   +20 more
openalex   +2 more sources

Vaspin identified as a DNA‐binding serpin with functional consequences for protease inhibition

The FEBS Journal, EarlyView.
Vaspin is a serpin that is expressed in skin, adipose tissue, and liver. It binds to single‐ and double‐stranded DNA with high affinity. This binding is unaffected by mutation of the known heparin‐binding site, accelerates the inhibition of the inflammatory protease KLK7, and may contribute to vaspin's nuclear localization.
Kevin Möhlis, Abibe Useini, Heike Betat, Sonja Bonin, Helen Broghammer, Rima Nuwayhid, Stefan Langer, Mario Mörl, Norbert Sträter, John T. Heiker   +9 more
wiley   +1 more source

The impact of protein S and tissue factor pathway inhibitor on coagulation, assessed with thrombin generation, in women starting combined oral contraceptives. [PDF]

Res Pract Thromb Haemost
Strandberg J, Nybo J, Gade IL, Kristensen SR.   +3 more
europepmc   +1 more source

Thrombin Generation Assay and Hemostatic Profile for Elucidating Hypercoagulability in Endogenous Canine Hyperadrenocorticism

, 2021
Silvia Eugenia Vargas Mora, Felipe Gazza Romão, Bruna dos Santos, Maria das Graçãs Carvalho Ferriani, Rita Carolina Figueiredo Duarte, Viviani De Marco Bernardes, Priscila A. Lopes, Regina Kiomi Takahira   +7 more
openalex   +2 more sources

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

The FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim, Kyeong‐Mi Bang, So Young An, Changkon Park, Ji‐Yeon Shin, Youngim Kim, Hyun Kyu Song, Jeong‐Yong Suh, Nak‐Kyoon Kim   +8 more
wiley   +1 more source

Characterization of antibodies for osteopontin fragments in rheumatoid arthritis [PDF]

, 2008
Sharif, Shadi
core   +1 more source

Physiologic impact of circulating RBC microparticles upon blood-vascular interactions [PDF]

, 2018
Doctor, Allan, Rogers, Stephen C, Said, Ahmed S   +2 more
core   +2 more sources