Results 201 to 210 of about 49,195 (253)

Comparative Investigation of Thromboelastometry and Thrombin Generation for Patients Receiving Direct Oral Anticoagulants or Vitamin K Antagonists. [PDF]

Diagnostics (Basel)
Tripodi A, Capecchi M, Scalambrino E, Clerici M, Scimeca B, Agosti P, Bucciarelli P, Artoni A, Peyvandi F.   +8 more
europepmc   +1 more source

A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine. [PDF]

Res Pract Thromb Haemost
Arachchillage DJ, Mobayen G, Laffan M, Randi AM, Ahnström J, Pericleous C.   +5 more
europepmc   +1 more source

Clot lysis time and thrombin generation in patients undergoing transcatheter aortic valve implantation. [PDF]

J Thromb Thrombolysis
Siniarski A, Gąsecka A, Krysińska K, Frydrych M, Nessler J, Gajos G.   +5 more
europepmc   +1 more source

Protein S contributes to the paradoxical increase in thrombin generation by low-dose dabigatran in the presence of thrombomodulin. [PDF]

Blood Coagul Fibrinolysis
Zhang C, Chen W, Zhang Y, Jiang T.
europepmc   +1 more source

Testosterone Therapy Does Not Affect Coagulation in Male Hypogonadism: A Longitudinal Study Based on Thrombin Generation.

J Clin Endocrinol Metab
Lanzi V, Indirli R, Tripodi A, Clerici M, Bonomi M, Cangiano B, Petria I, Arosio M, Mantovani G, Ferrante E.   +9 more
europepmc   +1 more source

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“Normal” Thrombin Generation

Blood, 1999
We have investigated the influence of alterations in plasma coagulation factor levels between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, factor VIII, factor V, protein C, protein S, antithrombin III (AT-III), and tissue factor pathway inhibitor (TFPI) as well as combinations of extremes, eg, 50 ...
Butenas, S., van't Veer, C., Mann, K. G.
openaire   +3 more sources

Thrombin generation tests

Thrombosis Research, 2011
The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin after initiation of coagulation. The thrombin generation curve, which is characterised by a lag phase followed by the formation and subsequent inhibition of thrombin,
Castoldi, Elisabetta, Rosing, Jan
openaire   +3 more sources

Thrombin generation and atherosclerosis

Journal of Thrombosis and Thrombolysis, 2013
Atherosclerosis is a major cause of mortality worldwide. The important role inflammation plays in atherosclerosis is evident through the participation of inflammatory cells in the development and progression of the disease. Thrombin is the central protease of the coagulation cascade, involved in the formation of a hemostatic plug to avoid severe ...
Kalz, Jana, ten Cate, Hugo, Spronk, Henri M. H.   +2 more
openaire   +3 more sources

Thrombin Generation

2013
Generation of thrombin has been established as the critical process leading to coagulation in vivo. Indeed, ex vivo markers of thrombin generation in patients have been useful in detecting thrombosis, while many standard global clot-time tests of haemostasis in blood or plasma samples are simple endpoint measures of the potential to generate thrombin ...
Leslie R, Berry, Anthony K C, Chan
openaire   +2 more sources

Antithrombotic Strategies Targeting Thrombin Activities, Thrombin Receptors and Thrombin Generation

Thrombosis and Haemostasis, 1997
Thrombin mediates acute vascular thrombosis and subsequent vascular lesion formation following mechanical denuding injury or spontaneous atherosclerotic plaque rupture. In the process of generating thrombin Factor VII/VIIa binds avidly with tissue factor (TF) exposed on cellular membranes, and coagulation serine proteases are sequentially cleaved via ...
L A, Harker, S R, Hanson, A B, Kelly
openaire   +2 more sources