Results 181 to 190 of about 3,896,793 (331)

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

Small, EarlyView.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Thrombin generation in pathophysiological conditions

Introduction: Thrombophilic conditions may be accompanied by increased thrombin generation (TG), especially during pregnancy when the increase in thrombin generation results from a series of changes in the haemostatic system.
Malíková, Ivana
core   +1 more source

Parameters of the thrombin generation test in pregnant women with preeclampsia: a systematic review. [PDF]

BMC Pregnancy Childbirth
do Nascimento Melo LC, Romana Alves Rios D, Rabelo Lopes L, Carvalho MDG, Sant'Ana Dusse LM, Nessralla Alpoim P, Barros-Pinheiro M.   +6 more
europepmc   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Duplication of the prothrombin gene is associated with a significant increase in thrombin generation. [PDF]

Res Pract Thromb Haemost
Siegemund A, Siegemund T, Bönigk H, Schlosser K, Konn K, Keil S, Petros S.   +6 more
europepmc   +1 more source

Integrated Methylome–Transcriptome Analysis Reveals Epigenomic Remodeling and Rho GTPase–Linked Immune–Epithelial Crosstalk in Atopic Dermatitis

Allergy, EarlyView.
Integrated methylome–transcriptome–microbiome analysis of AD skin identified thousands of DMRs. Rho GTPase signaling and actin–junctional programs emerged as central hubs integrating immune, epithelial, and microbial interactions in the pathogenesis of atopic dermatitis.
Tiina Skoog, Ying Yang, Peter Olah, Shintaro Katayama, Piia Karisola, Catherine Smith, Stephan Weidinger, Jonathan Barker, Antti Lauerma, Björn Andersson, Bernhard Homey, Nanna Fyhrquist, Juha Kere, Harri Alenius, MAARS Consortium, Francesca Levi‐Schaffer, Dario Greco, Stefanie Prast‐Nielsen, Vassili Soumelis, Sophia Tsoka, Jens M. Schröder, Frank O. Nestle, Philippe Hupé   +22 more
wiley   +1 more source

Intrinsic activated thrombin generation for treatment efficacy and monitoring of octocog alfa and emicizumab in severe hemophilia A. [PDF]

Res Pract Thromb Haemost
Urlings EH, Heubel-Moenen FCJI, van Oerle R, Hellenbrand DLS, van der Meijden PEJ, Hackeng TM, Cate HT, Nagy M, Henskens YMC, Spronk HMH.   +9 more
europepmc   +1 more source

Effect of Perfluorooctanesulfonic Acid on Fibrin Clot Properties and Thrombin Generation: Linking Environmental Pollution with Cardiovascular Diseases. [PDF]

J Cardiovasc Dev Dis
Kuciński J, Krawczyk K, Kieca K, Siniarski A, Ząbczyk M, Konduracka E.   +5 more
europepmc   +1 more source

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang, Claus H. Gravholt, Anne Skakkebæk, Anna‐Marie Bloch Münster, Yaseelan Palarasah   +4 more
wiley   +1 more source

Diagnostic performance of thrombin generation assay in patients with acute myocardial infarction. [PDF]

Caspian J Intern Med
Zekavat OR, Shojaie M, Sezavarian H, Rostami Ghorbani S, Dehghani SJ, Gerdabi J, Izadpanah P, Parand S, Haghpanah S.   +8 more
europepmc   +1 more source