Results 161 to 170 of about 3,896,793 (331)

DYNAMIC CHANGES IN THROMBIN GENERATION IN ABDOMINAL SEPSIS IN MICE.

, 2014
-Systemic inflammatory response syndrome and severe infections are associated with major derangements in the coagulation system. The purpose of this study was to examine the dynamic alterations in thrombin generation in abdominal sepsis. Abdominal sepsis
Wang, Yongzhi, Thorlacius, Henrik, Luo, Ling Tao, Zhang, Su, Norström, Eva, Braun, Oscar   +5 more
core   +1 more source

Droplet microfluidics: Enabling the tailored fabrication of hydrogel particles

Droplet, EarlyView.
Droplet microfluidics enables precise, versatile fabrication of hydrogel particles with controlled size, composition, and structure. This review summarizes fundamental principles, engineering strategies, and emerging applications, providing a framework for advancing microfluidic hydrogel technologies.
Zhongqiao Gan, Xu Hou
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Thrombin generation under flow in FVIII deficiencies.

, 2013
The average thrombin concentration within a thrombus was calculated using a spatial-temporal computational model of thrombus formation on 2.3 fmol TF/cm2. (A) Average thrombin concentration as a function of time for FVIII levels of 1, 5, 10, 20, and 100%.
Aaron L. Fogelson (483966), Karin Leiderman (483965), Abimbola A. Onasoga-Jarvis (483964), Marilyn J. Manco-Johnson (276376), Michael Wang (265591), Jorge A. Di Paola (276377), Keith B. Neeves (276368)   +6 more
core   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

Exploration, EarlyView.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang, Shuai Tian, Qinyu Han, Yulin Deng, Jiatao Zhang, Enqiang Linghu, Qianqian Chen, Zhimin Wang   +7 more
wiley   +1 more source

Bioactive Magnesium Silicate Activating Myocardial Energy Metabolism For Infarcted Myocardium Repair

Exploration, EarlyView.
ABSTRACT The heart is a highly energy‐dependent organ, developing bioenergy‐activating biomaterials to activate myocardial adenosine triphosphate (ATP) production and restore dysregulated energy homeostasis is a promising solution for its functional recovery.
Zhibin Liao, Chen Qin, Erhong Song, Chengbin Ding, Zhixu Wang, Yan Sun, Chen Song, Junjie Liu, Jingge Ma, Hongjian Zhang, Leyu Wang, Chengtie Wu   +11 more
wiley   +1 more source

“Nature's Polymer Reimagined: Conventional and Green Routes to Pectin, Its Bioactive Promise and Industrial Applications”

Food Chemistry International, EarlyView.
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique, Aunwesha Sahani, Md Morsaline Billah, Kazi Mohammed Didarul Islam   +3 more
wiley   +1 more source

Safety Profile of Sclerosing Agents in the Management of Low‐Flow Vascular Malformations of the Head and Neck—A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Low‐flow vascular malformations (LFVMs) of the head and neck, including venous and lymphatic malformations, represent a heterogeneous group of congenital anomalies frequently requiring intervention due to functional and esthetic impairment.
Riccardo Nocini, Carlotta Muneretto, Athena E. Arsie, Valerio Arietti, Benedetta Lorenzon, Alessandra Cinotti, Giacomo Colletti   +6 more
wiley   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source