Results 151 to 160 of about 49,195 (253)

Allosteric and ATP-Pocket BCR::ABL1 Inhibition In Vitro, and Characterising Ex Vivo Thrombo-Inflammatory Biomarkers and Thrombin Generation in Asciminib-Treated CML Patients. [PDF]

Int J Mol Sci
Omar MMA, Alanazi MA, Yeung DT, Hughes TP, Jackson DE.   +4 more
europepmc   +1 more source

High incidence of thrombin generation resistance to thrombomodulin in patients with unprovoked venous thromboembolism. [PDF]

Blood Vessel Thromb Hemost
Gris JC, Chea M, Nouvellon E, De Jouvancourt R, Fortier M, Bourguignon C, Laurent J, Bouvier S, Perez-Martin A.   +8 more
europepmc   +1 more source

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang, Claus H. Gravholt, Anne Skakkebæk, Anna‐Marie Bloch Münster, Yaseelan Palarasah   +4 more
wiley   +1 more source

Thrombin generation in HeartMate 3 patients on apixaban and vitamin K antagonists: Variability limits clinical applicability. [PDF]

JHLT Open
Van Edom CJ, Droogné W, Jacobs S, Jacquemin M, Van Laer C, Van Puyvelde J, Vlasselaers D, Vandersmissen K, Vanassche T, Meyns B.   +9 more
europepmc   +1 more source

Umbilical Cord Blood–Derived Extracellular Vesicles Enhance Neurovascular Regeneration and Improve Erectile Function in a Mouse Model of Bilateral Cavernous Nerve Injury

Andrology, EarlyView.
ABSTRACT Background Erectile dysfunction (ED) secondary to cavernous nerve injury (CNI), such as that occurring after radical prostatectomy, remains a significant clinical challenge, particularly among patients who do not respond to phosphodiesterase Type 5 inhibitors (PDE5i).
Minh Nhat Vo, Guo Nan Yin, Fitri Rahma Fridayana, Yan Huang, Limanjaya Anita, Ju‐Hee Kang, Ji‐Kan Ryu   +6 more
wiley   +1 more source

Feasibility to infer accurate fibrinogen concentrations from thrombin generation, prothrombin time, or Reptilase time waveforms. [PDF]

Res Pract Thromb Haemost
Arisz RA, Bakker B, van den Ham R, Ahmed A, Eikenboom JCJ, Schols SEM, de Maat MPM, SYMPHONY consortium@SYMPHONY_NL.   +7 more
europepmc   +1 more source

Uterus‐preserving surgery for placenta accreta spectrum: An expert, illustrated review of techniques and its outcomes

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Uterus‐preserving strategies for PAS include myometrial resection and leaving placenta in situ, differing in surgical principles, complications, and follow‐up. Myometrial resection offers definitive treatment with lower rates of delayed morbidity, while leaving the placenta in situ minimizes surgical risk but is associated with prolonged follow‐up ...
Pedro Viana Pinto, Albaro José Nieto‐Calvache, Rafael José Vieira, Abdalla Mousa, Hooman Soleymani majd, Rozi Aditya Aryananda, José Miguel Palacios‐Jaraquemada   +6 more
wiley   +1 more source

Baseline Thrombin Generation Test Does Not Predict Thrombotic Events in Acute Leukemia: A Monocentric Prospective Study. [PDF]

Mediterr J Hematol Infect Dis
Biglietto M, Mormile R, Bisegna ML, Laganà A, Faccini A, Papa A, Baldacci E, Santoro C, De Propris MS, Chistolini A.   +9 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Comparative <i>ex vivo</i> analysis of Mim8 in thrombin generation assays triggered by activated factor XI or tissue factor. [PDF]

Res Pract Thromb Haemost
Ong Clausen WH, Latendorf T, Stehr R, Ezban M, Lund J.   +4 more
europepmc   +1 more source