Results 131 to 140 of about 3,896,793 (331)
Advanced Science, EarlyView.A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li +11 more
wiley +1 more source
Increased thrombin generation after acute versus chronic coronary disease as assessed by the thrombin generation test [PDF]
, 2008 Atherosclerosis is the most common pathophysiologic substrate of coronary artery disease (CAD). Whereas plaque progression and arterial remodeling are critical components in chronic CAD, intracoronary thrombosis over plaque disruption is causally related
Zudaire, M. (Maite) +6 more
core
Comparing factor Xa and thrombin generation.
, 2013 Thrombin generation profiles from the same population, previously determined using the same methodology [15], are compared to their fXa profiles. Three pairs of overlapping individual thrombin generation profiles are shown on the left.
Frits R. Rosendaal (335481) +4 more
core +1 more source
Standardization and clinical utility of thrombin-generation assays
, 2008 Thrombin generation is a key process that determines the extent of a hemostatic plug or a thrombotic process. The ensuing thrombin burst is crucial for the formation of a stable fibrin clot.
Salvagno, Gian Luca, +2 more
core +2 more sources
Advanced Science, EarlyView.Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk +9 more
wiley +1 more source
Angewandte Chemie, EarlyView.A simple, rapid, and portable gold‐coated filter tip‐based assay (GFTA) is developed for bacterial detection. The GFTA leverages cleavable functional nucleic acid probes as molecular recognition elements to target RNase H2, a highly conserved bacterial endoribonuclease, enabling sensitive and specific colorimetric detection of bacterial pathogens ...
Jiuxing Li +4 more
wiley +2 more sources
Вестник хирургии имени И.И. Грекова, 2018 Generally recognized factor, which complicates the course of sepsis, is the development of hypercoagulation syndrome. The increase of thrombin coagulation indicates on the elevation of risk of thrombus formation in microcirculation vessels, which could ...
Kh. A. Gamzatov +9 more
doaj +1 more source
Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis
Advanced Science, EarlyView.ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu +26 more
wiley +1 more source
Advanced Science, EarlyView.An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu +8 more
wiley +1 more source
Continuous registration of thrombin generation in plasma:Its use for the determination of the thrombin potential [PDF]
, 1993 A method is described by which the time-course of thrombin generation in plasma can be obtained from a continuous optical density recording of p-nitroaniline (pNA) production in a 2:3 diluted plasma.
Kessels, H. +3 more
core +1 more source