Results 231 to 240 of about 100,897 (348)

TGFβ enhances platelet–breast‐cancer‐cell interaction and promotes platelet aggregation

The FEBS Journal, EarlyView.
TGFβ stimulation promotes EMT in MCF7 cells, increasing their ability to bind, activate, and aggregate PLT. This effect involves the upregulation of adhesion molecules Integrin‐αv and Galectin‐3. Inhibiting Integrin‐αv or Galectin‐3, through Cilengitide and GB1103, reduces PLT adhesion to MCF7 and PLT aggregation, suggesting a mechanism linking TGFβ ...
Margherita Genitoni, Lucia Merolle, Agnese Razzoli, Eleonora Maurizi, Gaia Gavioli, Roberto Baricchi, Chiara Marraccini, Davide Schiroli   +7 more
wiley   +1 more source

Thrombin Generation Assay to Support Hematologists in the Era of New Hemophilia Therapies. [PDF]

Int J Lab Hematol
Josset L, Rezigue H, Dargaud Y.
europepmc   +1 more source

D-dimer corrected for thrombin and plasmin generation is a strong predictor of mortality in patients with sepsis.

, 2020
Fabrizio Semeraro, Concetta T Ammollo, Pietro Caironi, Serge Masson, Roberto Latini, Mauro Panigada, Antonio Pesenti, Nicola Semeraro, Luciano Gattinoni, Mario Colucci   +9 more
openalex   +2 more sources

No correlation between thrombin generation and emicizumab levels: implications for monitoring emicizumab therapy. [PDF]

Res Pract Thromb Haemost
van der Zwet K, Roest M, Huskens D, Schutgens REG, van Vulpen LFD, Fischer K, Urbanus RT.   +6 more
europepmc   +1 more source

Relationships Between Homocysteine, Factor VIIa, and Thrombin Generation in Acute Coronary Syndromes [PDF]

, 2000
Mohamed Al-Obaidi, Helen Philippou, Peter Stubbs, Antonella Adami, Rajiv Amersey, Mark M. Noble, David A. Lane   +6 more
openalex   +1 more source

Post‑Marketing Surveillance of the Safety and Effectiveness of Emicizumab in Japanese Patients With Congenital Haemophilia A With Inhibitors

Haemophilia, EarlyView.
ABSTRACT Introduction The bispecific monoclonal antibody emicizumab was approved for prophylactic treatment of congenital haemophilia A (HA) in Japan in 2018. Aim To monitor long‐term safety and effectiveness of emicizumab, including appropriate concomitant use of bypassing agents (BPAs), in Japanese patients with congenital HA with inhibitors who ...
Midori Shima, Katsuyuki Fukutake, Masanori Matsumoto, Yoshihiko Sugimura, Chiaki Sugita, Lyu Ji, Mika Kawano, Tadashi Matsushita   +7 more
wiley   +1 more source

Age- and sex-dependency of thrombin generation parameters in the general Italian population: the Moli-sani study. [PDF]

Front Cardiovasc Med
Costanzo S, de Laat B, Di Castelnuovo A, van der Vorm L, De Curtis A, Cerletti C, Ninivaggi M, Donati MB, Iacoviello L, de Laat-Kremers R, Moli-sani investigators.   +10 more
europepmc   +1 more source

Thrombin Generation Kinetics are Predictive of Rapid Transfusion in Trauma Patients Meeting Critical Administration Threshold

, 2020
Taleen A. MacArthur, Grant M. Spears, Rosemary A. Kozar, Jing-fei Dong, Matthew Auton, Donald H. Jenkins, Kent R. Bailey, Aneel A. Ashrani, Mike J. Ferrara, Joseph M. Immermann, Timothy Halling, Myung S. Park   +11 more
openalex   +2 more sources

Acceptability and Determinants for Implementation of the EnzySystem, a Novel Near‐Patient Testing Platform for Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Coagulation testing in haemophilia A is limited by the scarcity of testing facilities capable of performing relevant assays. This issue incentivized the development of the EnzySystem for haemophilia A, a near‐patient testing platform aimed to measure Factor VIII activity and thrombin generation simultaneously within 1 h from 100 ...
Aernoud P. Bavinck, Kyle Davis, Lisa van Engelshoven, Monique G. van Lier, Tanja Hamacher, Nicole M. A. Blijlevens, Amy Shapiro, Saskia E. M. Schols, Waander L. van Heerde   +8 more
wiley   +1 more source

Correlation Between Thrombin Generation and Hepatic Fibrosis in Chronic Liver Diseases. [PDF]

Cureus
Vecerzan L, Maniu I, Cioca G.
europepmc   +1 more source