Bleeding Symptoms in Pediatric Patients with Congenital FVII Deficiency and Correlation to Thrombin Generation Assay Parameters: A Single-Center Retrospective Analysis. [PDF]
Di Felice G +8 more
europepmc +1 more source
Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna +7 more
wiley +1 more source
Pathogen‐reduced plasma, cryoprecipitate reduced for therapeutic plasma exchange
Abstract Background Therapeutic plasma exchange (TPE) for thrombotic thrombocytopenic purpura (TTP) and auto‐immune disorders involves repeated patient exposure to allogenic plasma with the risk of transfusion‐transmitted infection (TTI).
Florian Tupin +6 more
wiley +1 more source
In response to bacteria, neutrophils release extracellular vesicles capable of initiating thrombin generation through DNA-dependent and independent pathways. [PDF]
Whitefoot-Keliin KM +7 more
europepmc +1 more source
Abstract Objective To determine and compare the fixation strength of conjunctival pedicle flaps to cornea achieved via conventional ophthalmic suture and three different adhesive compounds. Animals Studied Ex vivo porcine globes. Procedures Following a 6 mm wide 500‐micron‐restricted depth lamellar keratectomy, conjunctival pedicle flaps were secured ...
Elodie M. VerHulst +4 more
wiley +1 more source
Plasma kallikrein supports FXII-independent thrombin generation in mouse whole blood. [PDF]
Wan J +13 more
europepmc +1 more source
The effect of thrombin inhibitors on coagulation activity and generation of activated protein C
Rikard Linder
openalex
From platelets to particles: Optimizing extracellular vesicle isolation in a National Blood Centre
Abstract Background and Objectives Platelet‐derived extracellular vesicles (PEVs) are submicron, membrane‐bound particles released upon platelet activation, with a recognized role in haemostasis, inflammation and immunoregulation. PEVs remain insufficiently characterized in blood products.
Y. Chintala +5 more
wiley +1 more source

