Results 271 to 280 of about 3,896,793 (331)
Comparative Investigation of Thromboelastometry and Thrombin Generation for Patients Receiving Direct Oral Anticoagulants or Vitamin K Antagonists. [PDF]
Tripodi A +8 more
europepmc +1 more source
A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine. [PDF]
Arachchillage DJ +5 more
europepmc +1 more source
Clot lysis time and thrombin generation in patients undergoing transcatheter aortic valve implantation. [PDF]
Siniarski A +5 more
europepmc +1 more source
Protein S contributes to the paradoxical increase in thrombin generation by low-dose dabigatran in the presence of thrombomodulin. [PDF]
Zhang C, Chen W, Zhang Y, Jiang T.
europepmc +1 more source
Thrombin Generation Assays (TGAs).
In recent years, there has been a revival of interest in a time-honored tool of the clotting trade: the thrombin generation curve or thrombin generation (TG) assay (TGA) as we now call it. Thrombin generation is a key coagulation process that determines the extent of a hemostatic plug or a thrombotic process. The recent development of newer tests based
G. Salvagno, E. Berntorp
semanticscholar +4 more sources
The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin after initiation of coagulation. The thrombin generation curve, which is characterised by a lag phase followed by the formation and subsequent inhibition of thrombin,
Castoldi, Elisabetta, Rosing, Jan
openaire +4 more sources
We have investigated the influence of alterations in plasma coagulation factor levels between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, factor VIII, factor V, protein C, protein S, antithrombin III (AT-III), and tissue factor pathway inhibitor (TFPI) as well as combinations of extremes, eg, 50 ...
Butenas, S., van't Veer, C., Mann, K. G.
openaire +4 more sources
Thrombin generation and atherosclerosis
Atherosclerosis is a major cause of mortality worldwide. The important role inflammation plays in atherosclerosis is evident through the participation of inflammatory cells in the development and progression of the disease. Thrombin is the central protease of the coagulation cascade, involved in the formation of a hemostatic plug to avoid severe ...
Kalz, Jana +2 more
openaire +4 more sources
Generation of thrombin has been established as the critical process leading to coagulation in vivo. Indeed, ex vivo markers of thrombin generation in patients have been useful in detecting thrombosis, while many standard global clot-time tests of haemostasis in blood or plasma samples are simple endpoint measures of the potential to generate thrombin ...
Leslie R, Berry, Anthony K C, Chan
openaire +3 more sources

