Assessment of Platelet Aggregation and Thrombin Generation in Patients with Familial Chylomicronemia Syndrome Treated with Volanesorsen: A Cross-Sectional Study. [PDF]
Calcaterra IL +10 more
europepmc +1 more source
Thrombin generation to evaluate the complex hemostatic balance of hemophilia A plasma containing direct oral anticoagulant and supplemented by factor VIII. [PDF]
Lamoine S +7 more
europepmc +1 more source
Abstract figure legend Illustration of cellular and molecular cross‐talk in atrial fibrillation. Left: a schematic of cardiac tissue showing cardiomyocytes, fibroblasts, adipocytes, inflammatory cells and the coagulation system. Right: direct and indirect cross‐talk between different cell types, with the impact of direct cross‐talk on action potential (
Zhenyu Dong +2 more
wiley +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Thrombomodulin is a stronger indicator of combined oral contraceptives-induced activated protein C pathway resistance in the thrombin generation test than activated protein C. [PDF]
Ninivaggi M +4 more
europepmc +1 more source
Narrative review of strategies for blood product shelf‐life extension
Transfusion, EarlyView.
Mike Akaraphanth +7 more
wiley +1 more source
Plasma Proteomic Profile of Chemotherapy‐Induced Severe Neutropenia: A Pilot Discovery Phase Study
Immune system, hemostasis, and protein metabolism are the major biological mechanistic effects affected by chemotherapy‐induced myelotoxicity treatment, which may underline tissue damage and systemic responses seen in patients' follow‐up treatment. ABSTRACT Transient severe neutropenia and thrombocytopenia are frequent during treatment of hematological
Leticia Queiroz da Silva +10 more
wiley +1 more source
Association between venous thromboembolism-associated genetic variants, coagulation factor levels, and thrombin generation potential. [PDF]
Han J +4 more
europepmc +1 more source

