Results 131 to 140 of about 200,052 (360)

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source

Renal Dysfunction Is an Independent Risk Factor for Poor Outcome in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis: A New Cutoff Value [PDF]

, 2017
Elyar Sadeghi‐Hokmabadi, Demet Funda Baş, Mehdi Farhoudi, Aliakbar Taheraghdam, Daryoush Savadi-Oskouei, Mohammad Yazdchi, Mazyar Hashemilar, Nevzat Üzüner, Reshad Mirnour, Ertuğrul Çolak, Atilla Özcan Özdemi̇r   +10 more
openalex   +1 more source

Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics

Annals of Neurology, EarlyView.
Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino, Elena Sagues, Carlos Dier, Diego Ojeda, Samantha Saenz‐Hinojosa, Sebastian Sanchez, Ariel Vargas, Linder Wendt, Maria Belen Torres, Emily Garces, Alex Hanson, Navami Shenoy, Connor Aamot, Susan A. Walsh, Anil K. Chauhan, Gowri Anil‐Peethambar, Santiago Ortega‐Gutierrez, Jay Kinariwala, Mohamed Elshikh, Amir Shaban, Enrique C. Leira, Osorio Lopes Abath Neto, Malik Ghannam, Edgar A. Samaniego   +23 more
wiley   +1 more source

Surgery versus thrombolysis for initial management of acute limb ischaemia.

Cochrane Database of Systematic Reviews, 2018
BACKGROUND Both peripheral arterial thrombolysis and surgery can be used in the management of peripheral arterial ischaemia. Much is known about the indications, risks, and benefits of thrombolysis. However, whether thrombolysis works better than surgery
Rosemary Darwood, D. Berridge, D. Kessel, I. Robertson, R. Forster   +4 more
semanticscholar   +1 more source

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

Annals of Neurology, EarlyView.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim, Mahmoud H. Mohammaden, Hend Abdelhamid, Marta Olive‐Gadea, Marc Rodrigo‐Gisbert, Manuel Requena, Johanna T. Fifi, James E. Siegler, Santiago Ortega‐Gutierrez, Mohamad Abdalkader, Ali Alaraj, Wei Hu, Thanh N. Nguyen, Diogo C. Haussen, Raul G. Nogueira   +14 more
wiley   +1 more source

Association of higher triglyceride–glucose index and triglyceride-to-high-density lipoprotein cholesterol ratio with early neurological deterioration after thrombolysis in acute ischemic stroke patients

Frontiers in Neurology
BackgroundInsulin resistance (IR) can predict the prognosis of patients suffering from cerebrovascular disorders. The triglyceride–glucose (TyG) index and triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio have been confirmed to be ...
Mingzhu Deng, Kangping Song, Wei Xu, Guohua He, Jue Hu, Hui Xiao, Nina Zhou, Sufen Chen, Guilan Xu, Yangping Tong, Dan Zhang, Zhen Wang, Fangyi Li   +12 more
doaj   +1 more source

Centralising and optimising decentralised stroke care systems: a simulation study on short-term costs and effects

BMC Medical Research Methodology, 2017
Background Centralisation of thrombolysis may offer substantial benefits. The aim of this study was to assess short term costs and effects of centralisation of thrombolysis and optimised care in a decentralised system. Methods Using simulation modelling,
Maarten M. H. Lahr, Durk-Jouke van der Zee, Gert-Jan Luijckx, Patrick C. A. J. Vroomen, Erik Buskens   +4 more
doaj   +1 more source

Requirement of heparin for arterial and venous thrombolysis with recombinant tissue-type plasminogen activator [PDF]

, 1991
HJ Rapold, HR Lu, ZM Wu, H Nijs, D Collen   +4 more
openalex   +1 more source

Risk factors of hemorrhagic transformation after intravenous thrombolysis with rt-PA in acute cerebral infarction

QJM : monthly journal of the Association of Physicians, 2019
BACKGROUND Intravenous thrombolysis is considered to be the standard reperfusion therapy for acute ischemic stroke, but its application is limited by high risk of hemorrhagic transformation (HT) after thrombolysis. AIM This study aimed to identify risk
R. Wang, J. Zeng, F. Wang, X. Zhuang, X. Chen, J. Miao   +5 more
semanticscholar   +1 more source

OCT‐Guided Distal Left Main Bifurcation PCI: Mid‐Term Outcomes From a Multicenter South‐Asian Registry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Optical coherence tomography (OCT)‐guided percutaneous coronary intervention (PCI) enhances treatment of complex coronary artery lesions, including left main (LM) disease, by enabling lesion morphology assessment and stent optimization, thereby reducing major adverse cardiac events (MACE).
Prathap Kumar, Shaneez Najmy, Manu Rajendran, Ali Shafeeq, Blessvin Jino   +4 more
wiley   +1 more source