Results 1 to 10 of about 4,572,461 (301)

Targeting Therapeutics Across the Blood Brain Barrier (BBB), Prerequisite Towards Thrombolytic Therapy for Cerebrovascular Disorders—an Overview and Advancements [PDF]

AAPS PharmSciTech, 2015
K. K. Pulicherla, Mahendra Kumar Verma
openalex   +2 more sources

Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy

Science Advances, 2021
Bioinspired nanovesicles enable activated platelet–targeted delivery of tissue plasminogen activator for effective thrombolysis. Clinical use of tissue plasminogen activator (tPA) in thrombolytic therapy is limited by its short circulation time and ...
Yu Huang, Boram Gu, Isabelle I. Salles‐Crawley, K. A. Taylor, Li Yu, Jie Ren, Xuhan Liu, M. Emerson, C. Longstaff, A. Hughes, S. Thom, X. Y. Xu, Rongjun Chen   +12 more
semanticscholar   +1 more source

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila, Eskandani, Morteza, Farhoudi, Mehdi, Mohammadian, Reza, Rafi, Mohammad, Zamanlu, Masumeh   +5 more
core   +2 more sources

Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]

, 2007
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R., Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +4 more sources

Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]

, 2009
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Cucchiara, B., Demchuk, A., Kasner, S.E., Lees, K.R., Levine, S.R., Lyden, P., Messe, S.R., Sansing, L., Tanne, D.   +8 more
core   +1 more source

Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Fourth Edition)

Regional anesthesia and pain medicine, 2018
(Reg Anesth Pain Med. 2018;43:263–309)The American Society of Regional Anesthesia and Pain Medicine (ASRA) convened its Fourth Consensus Conference on Regional Anesthesia and Anticoagulation in conjunction with the European Society of Anesthesiology (ESA)
T. Horlocker, E. Vandermeuelen, S. Kopp, W. Gogarten, L. Leffert, H. Benzon   +5 more
semanticscholar   +1 more source

Guidelines on fibrinogen assays [PDF]

, 2003
No abstract ...
Becker, Blanco, Blomback, Cambas, Chantarangkul, Chantarangkul, Chitolie, Chitolie, Clauss, Cremer, Cushman, De Cristofaro, De Maat, De Metz, Eliasson, Gaffney, Gordon D. O. Lowe, Hantgan, Haverkate, Hoffmann, Humphries, Ian J. Mackie, Jacobsson, Kitchen, Kluft, Lawrie, Lowe, Lowe, Ludlam, Machin, Mackie, Marder, MDA, MDA, Natelson, NCCLS, Nieuwenhuizen, Oosting, Palareti, Rampling, Ratnoff, Rosenson, Rossi, Samuel J. Machin, Steven Kitchen, Swain, Sweetnam, Sweetnam, Thompson, Van Der Bom, Vermylen, Whicher, World Health Organisation Report   +52 more
core   +1 more source

Tissue Plasminogen Activator-Porous Magnetic Microrods for Targeted Thrombolytic Therapy after Ischemic Stroke.

ACS Applied Materials and Interfaces, 2018
Tissue plasminogen activator (tPA) is the only FDA approved thrombolytic drug for acute ischemic stroke but concerns regarding its limitations remain.
Jiangnan Hu, Shengwei Huang, Lu Zhu, Weijie Huang, Yiping Zhao, K. Jin, Q. Zhuge   +6 more
semanticscholar   +1 more source

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Update on Thrombolytic Therapy in Acute Pulmonary Thromboembolism.

Eurasian Journal of Medicine, 2019
Thrombolytic treatment accelerates the dissolution of thrombus in acute pulmonary thromboembolism (PTE) and is potentially a lifesaving treatment. High-risk PTE is the clearest indication for this therapy, and its use in intermediate-risk cases is still ...
E. Uçar
semanticscholar   +1 more source