Results 191 to 200 of about 38,466 (239)
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Thrombolytic Therapy

Emergency Medicine Clinics of North America, 1995
If the electrocardiogram is diagnostic of acute myocardial infarction (AMI) in the patient complaining of typical chest pain, then indications and contraindications for thrombolytic therapy must be assessed immediately. The goal is to administer a thrombolytic agent within 30 to 60 minutes of presentation to the emergency department.
G P, Young, J R, Hoffman
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Thrombolytic therapy

Annals of Emergency Medicine, 1993
All patients with symptoms and ECG findings suggestive of acute myocardial infarction (AMI) should be considered for treatment with thrombolytic agents. The decision to use thrombolytic therapy is a clinical judgment based upon a weighing of the potential benefits versus the possible risks.
Eisenberg, M.   +5 more
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Thrombolytic therapy

Blood Reviews, 1989
The accepted role for thrombolytic therapy has until recently been limited because of its complexity and side-effects. It has generally been reserved for use systemically in a limited number of patients with acute, major pulmonary embolism or iliofemoral venous thrombosis, and locally in some patients with acute, peripheral arterial occlusion.
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Monitoring thrombolytic therapy

Progress in Cardiovascular Diseases, 1992
HROMBOLYTIC THERAPY for acute myocardial infarction (MI) now represents the standard of care for many patients. A large number of clinical trials have demonstrated improvement in survival and cardiac function following treatment of acute MI with thrombolytic agents,‘.’ and the use of thrombolytic therapy is rapidly spreading to community hospitals.
E G, Bovill, R, Becker, R P, Tracy
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Thrombolytic therapy for stroke

Current Opinion in Neurology, 1994
The physiology of thrombi and the pharmacology of thrombolytic drugs are under active study and improved regimens for the dosing of thrombolytic agents have been developed. In the setting of myocardial infarction, recently reported differences among thrombolytic agents have been slight, including the frequency of thrombolysis-associated hemorrhagic ...
T, Brott, J, Broderick, R, Kothari
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Advances in Thrombolytic Therapy

Drug Intelligence & Clinical Pharmacy, 1982
Streptokinase and urokinase are the two thrombolytic agents currently available in the United States. These drugs promote dissolution of thrombi by stimulating the conversion of plasminogen to plasmin, resulting in an overall “lytic state” in the blood. Recent clinical trials in patients with pulmonary emboli, deep vein thrombosis, arterial thrombosis,
D M, Rutkowski, W S, Burkle
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Applications of thrombolytic therapy

Intensive Care Medicine, 1998
Formation of a thrombus involves the aggregation of platelets, precipitation of fibrinogen into a fibrin meshwork and subsequent trapping of red blood cells. The coagulation cascades ensure that this process is initiated in response to a wide range of stimuli including local vessel trauma, endothelial damage and systemic inflammation.
N, Curzen, R, Haque, A, Timmis
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Thrombolytic therapy in the elderly

The Lancet, 2000
Elderly patients have the highest absolute risk of death following an acute myocardial infarction (MI); 16.1% for those aged between 65 and 74 years, and 25.3% for those older than 75 years. Therefore, this age-group potentially may benefit most from the use of thrombolytic therapy.
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Thrombolytic therapy in pregnancy

Journal of Thrombosis and Thrombolysis, 2006
Pregnancy due to its physiological changes is a procoagulant state. The rate of cardiac valve prosthesis thrombosis, deep venous thrombosis and pulmonary embolism are all increased. Thrombolytic therapy with tissue plasminogen activator (rt-PA) is an approved therapy for ischemic stroke, myocardial infarction, pulmonary embolism and thrombosis of ...
Georg, Leonhardt   +4 more
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Goals of thrombolytic therapy

The American Journal of Cardiology, 1991
In the past decade, mortality associated with acute myocardial infarction has been reduced to between 5% and 9% in selected groups of patients, largely due to use of early reperfusion. Thrombolytics combined with aggressive mechanical revascularization reduce the likelihood of death both during hospitalization and in the ensuing several years.
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