Results 191 to 200 of about 2,550,374 (236)
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Blood Reviews, 1989
The accepted role for thrombolytic therapy has until recently been limited because of its complexity and side-effects. It has generally been reserved for use systemically in a limited number of patients with acute, major pulmonary embolism or iliofemoral venous thrombosis, and locally in some patients with acute, peripheral arterial occlusion.
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The accepted role for thrombolytic therapy has until recently been limited because of its complexity and side-effects. It has generally been reserved for use systemically in a limited number of patients with acute, major pulmonary embolism or iliofemoral venous thrombosis, and locally in some patients with acute, peripheral arterial occlusion.
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A History of Thrombolytic Therapy
Journal of Endovascular Therapy, 2004 Thrombolytic therapy has been available for the last 5 decades, but the modern era of thrombolysis began in the early 1990s, with the execution of 3 multicenter trials designed to compare this potentially less invasive therapy to the then standard of care for acute limb ischemia, open surgical revascularization.
Shin Ishimaru, Kenneth Ouriel
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Monitoring thrombolytic therapy
Progress in Cardiovascular Diseases, 1992HROMBOLYTIC THERAPY for acute myocardial infarction (MI) now represents the standard of care for many patients. A large number of clinical trials have demonstrated improvement in survival and cardiac function following treatment of acute MI with thrombolytic agents,‘.’ and the use of thrombolytic therapy is rapidly spreading to community hospitals.
E G, Bovill, R, Becker, R P, Tracy
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Thrombolytic therapy for stroke
Current Opinion in Neurology, 1994The physiology of thrombi and the pharmacology of thrombolytic drugs are under active study and improved regimens for the dosing of thrombolytic agents have been developed. In the setting of myocardial infarction, recently reported differences among thrombolytic agents have been slight, including the frequency of thrombolysis-associated hemorrhagic ...
T, Brott, J, Broderick, R, Kothari
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Thrombolytic therapy in pregnancy
Journal of Thrombosis and Thrombolysis, 2006Pregnancy due to its physiological changes is a procoagulant state. The rate of cardiac valve prosthesis thrombosis, deep venous thrombosis and pulmonary embolism are all increased. Thrombolytic therapy with tissue plasminogen activator (rt-PA) is an approved therapy for ischemic stroke, myocardial infarction, pulmonary embolism and thrombosis of ...
Georg, Leonhardt +4 more
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Blood Reviews, 2001
T hrombolytic therapy represents part of a conjoint approach to achieving vascular reperfusion, based primarily on the use of fibrinolytic agents delivered systemically or directly into the offending thrombus and complemented by anticoagulation, antiplatelet, and even mechanical strategies.
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T hrombolytic therapy represents part of a conjoint approach to achieving vascular reperfusion, based primarily on the use of fibrinolytic agents delivered systemically or directly into the offending thrombus and complemented by anticoagulation, antiplatelet, and even mechanical strategies.
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Thrombolytic therapy in the elderly
The Lancet, 2000Elderly patients have the highest absolute risk of death following an acute myocardial infarction (MI); 16.1% for those aged between 65 and 74 years, and 25.3% for those older than 75 years. Therefore, this age-group potentially may benefit most from the use of thrombolytic therapy.
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Advances in Thrombolytic Therapy
Drug Intelligence & Clinical Pharmacy, 1982Streptokinase and urokinase are the two thrombolytic agents currently available in the United States. These drugs promote dissolution of thrombi by stimulating the conversion of plasminogen to plasmin, resulting in an overall “lytic state” in the blood. Recent clinical trials in patients with pulmonary emboli, deep vein thrombosis, arterial thrombosis,
D M, Rutkowski, W S, Burkle
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Applications of thrombolytic therapy
Intensive Care Medicine, 1998Formation of a thrombus involves the aggregation of platelets, precipitation of fibrinogen into a fibrin meshwork and subsequent trapping of red blood cells. The coagulation cascades ensure that this process is initiated in response to a wide range of stimuli including local vessel trauma, endothelial damage and systemic inflammation.
N, Curzen, R, Haque, A, Timmis
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Thrombolytic therapy in children
Thrombosis Research, 2006Thrombolysis is increasingly considered a treatment option in newborns and children with arterial and venous thromboembolic events, or occluded central venous lines. However, no uniform recommendations are available with regard to indications, drug of choice, route of administration, and dosing regimen.
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