Results 281 to 290 of about 4,589,938 (338)
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Thrombolytic therapy in children
Thrombosis Research, 2006Thrombolysis is increasingly considered a treatment option in newborns and children with arterial and venous thromboembolic events, or occluded central venous lines. However, no uniform recommendations are available with regard to indications, drug of choice, route of administration, and dosing regimen.
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Blood Reviews, 2001
T hrombolytic therapy represents part of a conjoint approach to achieving vascular reperfusion, based primarily on the use of fibrinolytic agents delivered systemically or directly into the offending thrombus and complemented by anticoagulation, antiplatelet, and even mechanical strategies.
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T hrombolytic therapy represents part of a conjoint approach to achieving vascular reperfusion, based primarily on the use of fibrinolytic agents delivered systemically or directly into the offending thrombus and complemented by anticoagulation, antiplatelet, and even mechanical strategies.
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Advances in Thrombolytic Therapy
Drug Intelligence & Clinical Pharmacy, 1982Streptokinase and urokinase are the two thrombolytic agents currently available in the United States. These drugs promote dissolution of thrombi by stimulating the conversion of plasminogen to plasmin, resulting in an overall “lytic state” in the blood. Recent clinical trials in patients with pulmonary emboli, deep vein thrombosis, arterial thrombosis,
D M, Rutkowski, W S, Burkle
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The American Journal of Cardiology, 1991
In the past decade, mortality associated with acute myocardial infarction has been reduced to between 5% and 9% in selected groups of patients, largely due to use of early reperfusion. Thrombolytics combined with aggressive mechanical revascularization reduce the likelihood of death both during hospitalization and in the ensuing several years.
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In the past decade, mortality associated with acute myocardial infarction has been reduced to between 5% and 9% in selected groups of patients, largely due to use of early reperfusion. Thrombolytics combined with aggressive mechanical revascularization reduce the likelihood of death both during hospitalization and in the ensuing several years.
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Applications of thrombolytic therapy
Intensive Care Medicine, 1998Formation of a thrombus involves the aggregation of platelets, precipitation of fibrinogen into a fibrin meshwork and subsequent trapping of red blood cells. The coagulation cascades ensure that this process is initiated in response to a wide range of stimuli including local vessel trauma, endothelial damage and systemic inflammation.
N, Curzen, R, Haque, A, Timmis
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Advances in thrombolytic therapy
Cardiovascular Drugs and Therapy, 1992Alteplase and saruplase are more fibrin-specific thrombolytic drugs than anistreplase. These and the thrombolytic drugs of the first generation (streptokinase and urokinase) have shortcomings and limitations. The prolonged intravenous maintenance infusions have been replaced by a bolus injection, accelerated infusions, or the combined intravenous ...
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Platelets and Thrombolytic Therapy
New England Journal of Medicine, 1990FIBRINOLYTIC therapy is a major advance in the treatment of occlusive vascular disease. Problems remain, however, including resistance to fibrinolytic therapy, delays in reperfusion, reocclusion after successful thrombolysis, and serious hemorrhage.1 2 3 Increasing evidence indicates that platelets have an important role in both delaying reperfusion ...
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