Results 21 to 30 of about 4,457,527 (301)
Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila+5 more
core +2 more sources
Tissue plasminogen activator (tPA) is the only FDA approved thrombolytic drug for acute ischemic stroke but concerns regarding its limitations remain.
Jiangnan Hu+6 more
semanticscholar +1 more source
Mismatch-based delayed thrombolysis: a meta-analysis [PDF]
<p><b>Background and Purpose</b>: Clinical benefit from thrombolysis is reduced as stroke onset to treatment time increases. The use of "mismatch" imaging to identify patients for delayed treatment has face validity and has been used in
Anthony J. Furlan+6 more
core +1 more source
Update on Thrombolytic Therapy in Acute Pulmonary Thromboembolism.
Thrombolytic treatment accelerates the dissolution of thrombus in acute pulmonary thromboembolism (PTE) and is potentially a lifesaving treatment. High-risk PTE is the clearest indication for this therapy, and its use in intermediate-risk cases is still ...
E. Uçar
semanticscholar +1 more source
Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R.+6 more
core +4 more sources
Susceptibility-weighted Imaging in Thrombolytic Therapy of Acute Ischemic Stroke
Objective: To provide a comprehensive and latest overview of susceptibility-weighted imaging (SWI) in the application of thrombolysis in acute ischemic stroke, and to update the decision-making effect and clinical value of SWI on identifying stroke ...
Lin Li+6 more
doaj +1 more source
Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Cucchiara, B.+8 more
core +1 more source
To determine whether utilization of emergency medical service (EMS) can increase use and expedite delivery of the thrombolytic therapy in acute ischemic stroke patients. Methods: We analyzed consecutive patients presenting to the emergency department (ED)
Ming-Ju Hsieh+8 more
doaj +1 more source
Tissue plasminogen activator-based clot busting: Controlled delivery approaches. [PDF]
Cardiovascular diseases are the leading cause of death worldwide. Thrombosis, the formation of blood clot (thrombus) in the circulatory system obstructing the blood flow, is one of the main causes behind various ischemic arterial syndromes such as ...
El-Sherbiny, IM, Elkholi, IE, Yacoub, MH
core +1 more source
Objective: Thrombolytic and anticoagulation therapy modalities are the possible treatment for submassive pulmonary embolism (PE). However, the indications are still the subject of debate.
Pınar Çimen+5 more
doaj +1 more source