Results 91 to 100 of about 17,882 (212)
Background: Endothelial dysfunction, hypercoagulability, hemolysis, and vasculopathy are involved in the pathogenesis of sickle cell leg ulcers (SCLUs).
Helen C. Okoye +8 more
doaj +1 more source
Acceleration of the thrombin inactivation of single chain urokinase-type plasminogen activator (pro-urokinase) by thrombomodulin [PDF]
The in vitro effects of thrombomodulin on the inactivation of single chain urokinase-type plasminogen activator (scu-PA) by thrombin were investigated by incubating scu-PA with varying concentrations of human thrombin, in both the absence and presence of
Groeneveld, E. +2 more
core +1 more source
Van Tri Nguyen,1,2 Hong Ngoc Nguyen-Phan,1 That Ngoc Ton,3 Bui Bao Hoang1 1Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam; 2Department of Anesthesiology of Hue International Medical Center, Hue
Nguyen VT +3 more
core
Detection and quantification of thrombomodulin in human semen
The presence of fibrin degradation products, thrombin-like enzyme, prothrombin fragments, thrombin-activatable fibrinolysis inhibitor, plasmin and other active components of blood coagulation and fibrinolysis in seminal plasma has been reported.
Cooper, Alan +5 more
core +1 more source
BackgroundThe mechanism by which combined oral contraceptives (COCs) lead to hypercoagulation is not fully understood, although activated protein C (APC) pathway resistance has been implicated.
Marisa Ninivaggi +6 more
doaj +1 more source
Background Venous thromboembolic events (VTEs) are the second‐leading cause of death in cancer patients, with an incidence of 5%–17% in lymphoma patients, particularly higher in those with non‐Hodgkin lymphoma (NHL). Existing risk assessment models (RAMs)
Wen Li +11 more
doaj +1 more source
Xingping Zhou,1,* Jinjin Luo,1,* Xi Liang,1,2 Peng Li,1 Keke Ren,1 Dongyan Shi,1,2 Jiaojiao Xin,1,2 Jing Jiang,1,2 Jiaxian Chen,1 Lulu He,1 Hui Yang,1 Shiwen Ma,1 Bingqi Li,1 Jun Li1,2 1State Key Laboratory for Diagnosis and Treatment of ...
Zhou X +13 more
doaj
Mutations in the thrombomodulin gene are rare in patients with severe thrombophilia
Because thrombomodulin plays a key role in the protein C pathway, we evaluated the contribution of thrombomodulin gene mutations to venous thrombosis.
F. Rodeghiero +4 more
core +1 more source
Thrombomodulin (TM) is a critical biomarker for endothelial dysfunction, yet there is currently no simple and rapid detection method, such as immunochromatographic assay (ICA).
Jie Liu +5 more
doaj +1 more source

