Results 111 to 120 of about 19,999 (193)

Efficacy and safety of high doses of eltrombopag for treating adult immune thrombocytopenia: Results from a multicentre retrospective cohort study

British Journal of Haematology, Volume 209, Issue 4, Page 1937-1940, October 2026.
Salomé Dahan, Stéphanie Guillet, Olivier Fain, Delphine Gobert, Stéphane Cheze, Florent Broca, Bertrand Godeau, Marc Michel   +7 more
wiley   +1 more source

Eltrombopag for the treatment of aplastic anemia: current perspectives

Drug Design, Development and Therapy, 2016
Su Han Lum, John D GraingerDepartment of Blood and Marrow Transplant, Royal Manchester Children’s Hospital, Manchester, UK Abstract: Aplastic anemia (AA) is a potential life-threatening hematopoietic stem cell (HSC) disorder resulting in cytopenia.
Lum SH, Grainger JD
doaj  

Thrombopoietin, the Primary Regulator of Platelet Production: From Mythos to Logos, a Thirty-Year Journey

Biomolecules
Thrombopoietin, the primary regulator of blood platelet production, was postulated to exist in 1958, but was only proven to exist when the cDNA for the hormone was cloned in 1994.
Kenneth Kaushansky
doaj   +1 more source

Relevance of anti‐thyroperoxidase antibodies in immune thrombocytopenia in adults: A single‐centre cohort study

British Journal of Haematology, Volume 209, Issue 4, Page 1941-1944, October 2026.
Nicolas Duhamel, Marie Ottavi, Sarah Lechtman, Nihal Martis, Charlotte Hinault‐Boyer, Julie Merindol, Pierre‐Yves Jeandel, Michael Levraut   +7 more
wiley   +1 more source

Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation.

, 2009
Hereditary thrombocythemia is a rare autosomal dominant disorder caused by mutations in either the thrombopoietin gene (TPO) or its receptor c-MPL. TPO mutations described so far lead to thrombopoietin overproduction through increased translation of m ...
CARONE, SIMONA, MAGINI, PAMELA, GRAZIANO, CLAUDIO, PESSION, ANDREA, SERI, MARCO, ROMEO, GIOVANNI, PANZA, EMANUELE, Marino F   +7 more
core   +1 more source

Spotlight on romiplostim in the treatment of children with chronic immune thrombocytopenia: design, development, and potential place in therapy

Drug Design, Development and Therapy, 2017
David Buchbinder, Diane Nugent, Loan Hsieh Division of Hematology, CHOC Children’s Hospital and UC Irvine Medical Center, CA, USA Abstract: Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia.
Buchbinder D, Nugent D, Hsieh L
doaj  

Monoclonal anti-thrombopoietin antibodies generated by genetic immunization

, 2006
Thrombopoietin (TPO) is a megakaryocyte growth and differentiation factor that is currently being investigated as a therapeutic for cancer patients undergoing myelosuppressive chemotherapy.
K S Kim, H J Kang, N K Lim, K S Inn, Hyo Jeong Hong, S Y Kim, S Lee, J H Kim   +7 more
core   +1 more source

Thrombopoietin concentrations in the ascitic fluid and plasma of patients with chronic liver diseases

, 2006
Plasma thrombopoietin levels in several studies in a variety of chronic liver diseases reveal conflicting results. The place of thrombopoietin in the pathobiological basis of ascites associated with chronic liver diseases has not been elucidated.
Aksoy, Duygu Y., Ozturk, Mustafa, Bavbek, Nuket, Babali, Aysegul, HAZNEDAROĞLU, İBRAHİM CELALETTİN, Kirazli, Serafettin, KOŞAR, ALİ   +6 more
core  

Effects of thrombopoietin on the protection against doxorubicin-induced cardiotoxicity. [PDF]

, 2006
To Man Yin.Thesis (M.Phil.)--Chinese University of Hong Kong, 2006.Includes bibliographical references (leaves 85-105).Abstracts in English and Chinese.Abstract (in English) --- p.i(in Chinese) --- p.ivAcknowledgements --- p.viPublications --- p ...

core  

Use of Immunosuppression, Romiplostim, and Splenectomy to Achieve Remission in a British Shorthair Cat With Primary Immune‐Mediated Thrombocytopenia

Journal of Veterinary Internal Medicine
A 2‐year‐old female spayed British Shorthair cat was diagnosed with immune‐mediated thrombocytopenia (ITP) after presenting with a 3‐week history of gastrointestinal bleeding and anemia.
Josh M. Kennils, Helen E. Wilson
doaj   +1 more source