Results 21 to 30 of about 15,012 (140)
The FASEB Journal, Volume 40, Issue 16, 31 August 2026.Magnesium (Mg2+) attenuates renal injury in ischemia–reperfusion and radiation‐induced kidney injury models in association with reduced DNA damage response markers, cellular senescence, inflammation, and fibrosis. Mg2+ treatment is associated with reduced H3K4me3 enrichment at the p16INK4a promoter, attenuation of senescence‐associated pathways, and ...
Makoto Matsubara +12 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, Volume 16, Issue 8, Page 1509-1526, August 2026.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
American Journal of Hematology, Volume 101, Issue 8, Page 1954-1968, August 2026.ABSTRACT Limited data exist on how patients and physicians perceive immune thrombocytopenia (ITP) symptoms and treatment‐related burden. I‐WISh (ITP World Impact Survey) 2.0 surveyed 1018 patients and 431 physicians in 15 countries to characterize the impact of ITP and its treatments on patients.
Nichola Cooper +17 more
wiley +1 more source
Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham +8 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.ABSTRACT Mechanistic PK/PD models represent complex biological systems in which model parameters are in nonlinear, multidimensional parameter spaces and often require robust optimization informed by experimental data, making parameter estimation a critical yet challenging aspect of pharmacometric analysis.
Dongjin Lee, Chih‐Wei Lin
wiley +1 more source
Clinical outcome, imaging and histopathological findings of liver cirrhosis in dogs
Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.Abstract Cirrhosis is a severe and irreversible condition resulting from chronic liver injury, characterised by extensive fibrosis and regenerative nodules. This report describes three dogs with cirrhosis. The main clinical findings included ascites, reduced body condition score and inappetence. Anaemia, thrombocytopenia, hypoalbuminaemia, and elevated
Wanderson Feliciano Duarte da Silva +4 more
wiley +1 more source
The association of thrombocytopenia with haematological malignancy
British Journal of Haematology, Volume 209, Issue 2, Page 441-443, August 2026.This review article discusses the interplay of immune dysregulation, clonality, and immunosuppressive therapies in immune thrombocytopenia and how this links to the risk of misattribution versus the development of haematological malignancy. Unresolved questions and directions for future research are also discussed. Isolated thrombocytopenia is commonly
Abi Vijenthira +2 more
wiley +1 more source