Results 111 to 120 of about 775,077 (341)

Dual‐Energy CT‐Based Assessment of Thrombotic Heterogeneity for Predicting Stroke Source and Response to Machine Thrombectomy: A Step Toward Visualization Thrombus Treatment

Advanced Science, EarlyView.
The research indicates that dual energy CT scanning can accurately predict the stroke source and clinical outcomes by analyzing thrombus heterogeneity. Based on histopathological analysis of thrombus components, these scans are better able to display thrombus details than standard CT scans, which is helpful for the development of visual navigation ...
Jingxuan Jiang, Sijia Wang, Fan Xiao, Hongmei Gu, Mingkang Wang, Hao Tian, Baohui Guan, Kai Sheng, Yijia Xiong, Huilin Zhao, Minda Li, Li Xu, Zheng Sun, Haiyan Du, Wenxian Du, Yuehua Li   +15 more
wiley   +1 more source

Steroids and Malignancy Increase Local Heparanase and Decrease Markers of Osteoblast Activity in Bone Tissue Microcirculation

Biomolecules
Bone metastasis and steroids are known to activate the coagulation system and induce osteoporosis, pathological bone fractures, and bone pain. Heparanase is a protein known to enhance the hemostatic system and to promote angiogenesis, metastasis, and ...
Keren Asayag, Eli Peled, Mai Assalia, Yonatan Crispel, Chen Yanovich, Haim Cohen, Anat Keren-Politansky, Yona Nadir   +7 more
doaj   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source

Heparin and Sympathetic Block in Treatment of Venous Thrombosis [PDF]

, 1957
W Rudowski
openalex   +1 more source

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

Advanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li, Lei Zhu, Zhaohuai Li, Yihan Zhang, Genxian Zhang, Xuening Peng, Dongting Wu, Qi Jiang, Rong Wang, Renbing Jia, Song Guo Zheng, Wenru Su   +11 more
wiley   +1 more source

β-hydroxybutyrate suppresses pathological changes of blood-induced arthropathy in rats

Scientific Reports
Arthropathy is a common complication in haemophilia and decreases quality of life. It has been known that concentrations of β-hydroxybutyrate (BHB) in blood are increased by a ketogenic diet, and elevated levels of circulating BHB restricts the ...
Ryohei Kawasaki, Asuka Sakata, Kohei Tatsumi, Seiji Mitani, Maiko Takeda, Shogo Kasuda, Naoki Matsumoto, Suguru Harada, Tetsuhiro Soeda, Yukiko Nishida, Yasushi Yoshimura, Midori Shima   +11 more
doaj   +1 more source

UNILATERAL RETINAL CHANGES in CEREBRAL HAeMORRHAGE, EMBOLISM, and THROMBOSIS [PDF]

, 1898
R. T. Williamson
openalex   +1 more source

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

Advanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen, Yujie Zhu, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, Lemin Zheng, Liangwan Chen   +18 more
wiley   +1 more source

THE CONDITION OF THE BLOOD IN HEMOPHILIA, THROMBOSIS AND PURPURA [PDF]

, 1914
W. H. Howell
openalex   +1 more source

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Advanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source