Results 61 to 70 of about 3,493 (184)

Prediction and analysis of higher-order coiled-coils:Insights from proteins of the extracellular matrix, tenascins and thrombospondins

, 2013
α-Helical coiled-coil domains (CCDs) direct protein oligomerisation in many biological processes and are of great interest as tools in protein engineering.
Woolfson, Derek N, Adams, Josephine C, Vincent, Thomas L   +2 more
core   +1 more source

Neuronal pentraxins mediate synaptic refinement in the developing visual system [PDF]

, 2006
Peer ...
Worley, Paul, Rentería, René,, Cho, Richard,, Prezioso, Jennifer,, Malenka, Robert C., Susman, Michael, Nakamoto, Masaru,, Susman, Michael W., Copenhagen, David,, Malenka, Robert,, Perin, Mark,, Liu, Xiaoquin, Huberman, Andrew, Huberman, Andrew,, Ullian, Erik M., Liu, Xiaoqin,, Nakamoto, Masaru, Perin, Mark S., Renteria, Rene C., Xu, Weifeng, Stokes, Caleb C., Peachey, Neal S., Ball, Sherry,, Stellwagen, David,, Cho, Richard, Peachey, Neal, Huberman, Andrew D., Stokes, Caleb,, Bjartmar, Lisa, Ullian, Erik, Worley, Paul,, Chapman, Barbara, Ullian, Erik,, Bjartmar, Lisa,, Chapman, Barbara,, Prezioso, Jennifer, Barres, Ben, Stellwagen, David, Ball, Sherry, Liu, Xiaoqin, Stokes, Caleb, Copenhagen, David, Malenka, Robert, Renterıa, Rene, Perin, Mark, Xu, Weifeng,, Barres, Ben A., Peachey, Neal,, Susman, Michael,, Barres, Ben,   +49 more
core   +1 more source

Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.

PLoS ONE, 2016
Thrombospondin 1 and thrombospondin 2 (THBS1 and THBS2) share similar multifunctional domains, and are known to be antiangiogenic. However, the expression pattern of THBS1 and THBS2 is different, and the specific role of THBS2 in different subtypes of ...
Tzu-Yang Weng, Chih-Yang Wang, Yu-Hsuan Hung, Wei-Ching Chen, Yi-Ling Chen, Ming-Derg Lai   +5 more
doaj   +1 more source

Thrombospondins:Conserved mediators and modulators of metazoan extracellular matrix [PDF]

This review provides a personal overview of significant scientific developments in the thrombospondin field during the course of my career. Thrombospondins are multidomain, multimeric, calcium-binding extracellular glycoproteins with context-specific ...
Adams, Josephine C
core   +1 more source

BDNF Pretreatment of Human Embryonic-Derived Neural Stem Cells Improves Cell Survival and Functional Recovery after Transplantation in Hypoxic–Ischemic Stroke

Cell Transplantation, 2015
Intra-arterial neural stem cell (NSC) therapy has the potential to improve long-term outcomes after stroke. Here we evaluate if pretreatment of NSCs with brain-derived neurotrophic factor (BDNF) prior to transplantation improves cell engraftment and ...
Sahar Rosenblum, Tenille N. Smith, Nancy Wang, Joshua Y. Chua, Erick Westbroek, Kendrick Wang, Raphael Guzman M.D.   +6 more
doaj   +1 more source

Glial control of synaptogenesis

, 2012
Though all communication between neurons occurs through synapses, we know surprisingly little about the mechanisms inducing their formation. In this issue of Cell, Barres and colleagues (Christopherson et al., 2005) demonstrate that glial-derived ...
Freeman, Marc R.
core   +2 more sources

Evolutionary divergence and functions of the ADAM and ADAMTS gene families

Human Genomics, 2009
The 'A-disintegrin and metalloproteinase' (ADAM) and 'A-disintegrin and metalloproteinase with thrombospondin motifs' (ADAMTS) genes make up two similar, yet distinct, gene families.
Brocker Chad N, Vasiliou Vasilis, Nebert Daniel W   +2 more
doaj   +1 more source

Thrombospondins and remodeling of the tumor microenvironment

, 2018
Vascular remodeling defines cancer growth and aggressiveness. Although cancer cells produce pro-angiogenic signals, the fate of angiogenesis critically depends on the cancer microenvironment.
Muppala, Santoshi, Gajeton, Jasmine, Stenina-Adognravi, Olga   +2 more
core  

Whence Thrombospondin? [PDF]

Cancer Biology & Therapy, 2004
Andrei, Thomas-Tikhonenko, M Luisa, Iruela-Arispe   +1 more
openaire   +2 more sources

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma

Neurobiology of Disease
Thrombospondins (TSPs) are astrocyte-secreted extracellular matrix proteins that play key roles as regulators of synaptogenesis in the central nervous system.
Haifeng Shu, Isabel Parada, Alex Delgado, David A. Prince, Feng Gu   +4 more
doaj   +1 more source